Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
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Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptorsBinary drugs: conjugates of purines and a peptide that bind to both adenosine and substance P receptorsEffect of selective agonists and antagonists on atrial adenosine receptors and their interaction with Bay K 8644 and [3H]-nitrendipine.Use of the triazolotriazine [3H]ZM 241385 as a radioligand at recombinant human A2B adenosine receptors.Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptorsAdenosine receptor prodrugs: towards kidney-selective dialkylxanthinesProbing the adenosine receptor with adenosine and xanthine biotin conjugatesFunctionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cellsApparent affinity of some 8-phenyl-substituted xanthines at adenosine receptors in guinea-pig aorta and atriaAdenosine analogs with covalently attached lipids have enhanced potency at A1-adenosine receptors"Cleavable trifunctional" approach to receptor affinity labeling: chemical regeneration of binding to A1-adenosine receptorsA binding site model and structure-activity relationships for the rat A3 adenosine receptorStructure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonistsStructure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.Trifunctional agents as a design strategy for tailoring ligand properties: irreversible inhibitors of A1 adenosine receptors.Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs).Xanthines as adenosine receptor antagonists.XAC, a functionalized congener of 1,3-dialkylxanthine, antagonizes A1 adenosine receptor-mediated inhibition of renin secretion in vitro.GPCR ligand dendrimer (GLiDe) conjugates: adenosine receptor interactions of a series of multivalent xanthine antagonistsA [3H]amine congener of 1,3-dipropyl-8-phenylxanthine. A new radioligand for A2 adenosine receptors of human platelets.Evidence that a novel 8-phenyl-substituted xanthine derivative is a cardioselective adenosine receptor antagonist in vivo.A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo.[3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors.Adenosine A1 and A2 receptors: structure--function relationshipsMolecular probes for extracellular adenosine receptors.Probing adenosine receptors using biotinylated purine derivatives.Xanthine functionalized congeners as potent ligands at A2-adenosine receptors.Functionalized congeners of 1,4-dihydropyridines as antagonist molecular probes for A3 adenosine receptorsA functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.8-Substituted xanthines as antagonists at A1- and A2-adenosine receptors.Adenosine receptor-induced second messenger production in adult guinea-pig cerebellumAdenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.Purine nucleosides and nucleotides as central nervous system modulators. Adenosine as the prototypic paracrine neuroactive substance.A1- and A2-selective adenosine antagonists: in vivo characterization of cardiovascular effectsFurther characterization of the renovascular effects of N6-cyclohexyladenosine in the isolated perfused rat kidney.Adenosine derivatives with N6-alkyl, -alkylamine or -alkyladenosine substituents as probes for the A1-receptor.Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding.Sole activation of three luminal adenosine receptor subtypes in different parts of coronary vasculature.Solubilities of adenosine antagonists determined by radioreceptor assay.
P2860
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P2860
Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Functionalized congeners of 1, ...... inity for adenosine receptors.
@ast
Functionalized congeners of 1, ...... inity for adenosine receptors.
@en
type
label
Functionalized congeners of 1, ...... inity for adenosine receptors.
@ast
Functionalized congeners of 1, ...... inity for adenosine receptors.
@en
prefLabel
Functionalized congeners of 1, ...... inity for adenosine receptors.
@ast
Functionalized congeners of 1, ...... inity for adenosine receptors.
@en
P2093
P2860
P356
P1476
Functionalized congeners of 1, ...... inity for adenosine receptors.
@en
P2093
K A Jacobson
W L Padgett
P2860
P304
P356
10.1021/JM00147A038
P407
P577
1985-09-01T00:00:00Z