Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.
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The Regulation of Cellular Responses to Mechanical Cues by Rho GTPasesThe focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxisEnvironmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor betaA Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail.Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stressTumor mechanics and metabolic dysfunction.Matrix metalloproteinases as breast cancer drivers and therapeutic targets.A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients.Topographic confinement of epithelial clusters induces epithelial-to-mesenchymal transition in compliant matricesTumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinomaPushing, pulling, and squeezing our way to understanding mechanotransductionInterstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin.A 3D in vitro model to explore the inter-conversion between epithelial and mesenchymal states during EMT and its reversion.Extracellular matrix proteins regulate epithelial-mesenchymal transition in mammary epithelial cells.Role of NADPH oxidase-mediated reactive oxygen species in podocyte injury.The fate of the primary cilium during myofibroblast transitionMechanotransduction in cancer.The importance of matrix metalloproteinase-3 in respiratory disorders.Mouse Nudt13 is a Mitochondrial Nudix Hydrolase with NAD(P)H Pyrophosphohydrolase Activity.Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells.The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma.Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways.The role of small GTPases of the Rho/Rac family in TGF-β-induced EMT and cell motility in cancer.Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium.Towards a personalized surgical margin for breast conserving surgery-Implications of field cancerization in local recurrence.Scattering of Cell Clusters in ConfinementTherapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.Fibronectin fibrils regulate TGF-β1-induced Epithelial-Mesenchymal Transition.Microfluidic Programming of Compositional Hydrogel Landscapes.Effects of Matrix Stiffness on the Morphology, Adhesion, Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells.A 3D Culture Model to Study How Fluid Pressure and Flow Affect the Behavior of Aggregates of Epithelial Cells.The Bioelectric Code: Reprogramming Cancer and Aging From the Interface of Mechanical and Chemical Microenvironments.Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1.A Soft Microenvironment Protects from Failure of Midbody Abscission and Multinucleation Downstream of the EMT-Promoting Transcription Factor Snail.
P2860
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P2860
Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@ast
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@en
type
label
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@ast
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@en
prefLabel
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@ast
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@en
P2093
P2860
P356
P1476
Matrix compliance regulates Ra ...... helial-mesenchymal transition.
@en
P2093
Cecillia Lui
Celeste M Nelson
Derek C Radisky
KangAe Lee
Magdalena A Cichon
Qike K Chen
P2860
P304
P356
10.1091/MBC.E12-02-0166
P577
2012-08-23T00:00:00Z