Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins
about
Particle-rich cytoplasmic structure (PaCS): identification, natural history, role in cell biology and pathologyRUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.Selective autophagy mediated by autophagic adapter proteinsBAG-6 is essential for selective elimination of defective proteasomal substratesIn vivo accumulation of Helicobacter pylori products, NOD1, ubiquitinated proteins and proteasome in a novel cytoplasmic structureDifferent Polyubiquitinated Bodies in Human Dendritic Cells: IL-4 Causes PaCS During Differentiation while LPS or IFNα Induces DALIS During MaturationMisfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complexThe Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.Phosphorylation of NBR1 by GSK3 modulates protein aggregation.Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implicationsNuclear translation visualized by ribosome-bound nascent chain puromycylation.The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates.Premature translational termination products are rapidly degraded substrates for MHC class I presentationNrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation.Granulostasis: Protein Quality Control of RNP Granules.Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.p62/SQSTM1 enhances NOD2-mediated signaling and cytokine production through stabilizing NOD2 oligomerization.PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors.Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy.Cross-presentation: dendritic cells and macrophages bite off more than they can chew!Differential use of autophagy by primary dendritic cells specialized in cross-presentationTransient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress.Ubiquitin-proteasome-rich cytoplasmic structures in neutrophils of patients with Shwachman-Diamond syndromeAssociation of translation factor eEF1A with defective ribosomal products generates a signal for aggresome formation.Basic concepts of immune response and defense development.Dendritic cells, DRiPs, and DALIS in the control of antigen processing.Regulation of translation is required for dendritic cell function and survival during activation.Viruses and dendritic cells: enemy mine.LC3 fluorescent puncta in autophagosomes or in protein aggregates can be distinguished by FRAP analysis in living cellsActivation of Autophagy Pathway Suppresses the Expression of iNOS, IL6 and Cell Death of LPS-Stimulated Microglia Cells.Polyubiquitin chains: functions, structures, and mechanisms.Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses.Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells.Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors.The role of spartin and its novel ubiquitin binding region in DALIS occurrence.Fighting disease by selective autophagy of aggregate-prone proteins.The role of the proteasome in the generation of MHC class I ligands and immune responses.Translating DRiPs: progress in understanding viral and cellular sources of MHC class I peptide ligands.Aggrephagy: selective disposal of protein aggregates by macroautophagy.BAG6/BAT3: emerging roles in quality control for nascent polypeptides.
P2860
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P2860
Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Dendritic cell aggresome-like ...... synthesized defective proteins
@ast
Dendritic cell aggresome-like ...... synthesized defective proteins
@en
type
label
Dendritic cell aggresome-like ...... synthesized defective proteins
@ast
Dendritic cell aggresome-like ...... synthesized defective proteins
@en
prefLabel
Dendritic cell aggresome-like ...... synthesized defective proteins
@ast
Dendritic cell aggresome-like ...... synthesized defective proteins
@en
P2093
P2860
P50
P356
P1476
Dendritic cell aggresome-like ...... synthesized defective proteins
@en
P2093
Didier Marguet
Jacek Bania
Vincent Ferrand
Voahirana Camosseto
P2860
P304
P356
10.1083/JCB.200312073
P407
P577
2004-02-23T00:00:00Z