Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.
about
KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomasPaxillin comes of ageFAK and paxillin, two potential targets in pancreatic cancerVinculin and metavinculin: oligomerization and interactions with F-actinThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationVinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission.Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophyPaxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasionAFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancersPaxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoAiTRAQ-based proteomics reveals novel members involved in pathogen challenge in sea cucumber Apostichopus japonicusCaM kinase II delta2-dependent regulation of vascular smooth muscle cell polarization and migrationSpatial distribution and functional significance of activated vinculin in living cellsVinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytesIdentification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.Vinculin controls focal adhesion formation by direct interactions with talin and actin.Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesionsAlterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner.Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration.Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin.GnRH Induces ERK-Dependent Bleb Formation in Gonadotrope Cells, Involving Recruitment of Members of a GnRH Receptor-Associated Signalosome to the Blebs.A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells.What is vinculin needed for in platelets?Vinculin facilitates cell invasion into three-dimensional collagen matrices.Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.A molecular dynamics investigation of vinculin activation.Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo.Activation of membrane androgen receptors in colon cancer inhibits the prosurvival signals Akt/bad in vitro and in vivo and blocks migration via vinculin/actin signaling.Nanotopographical control of stem cell differentiation.Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin.Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancerDown-regulation of vinculin upon MK886-induced apoptosis in LN18 glioblastoma cellsMicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expressionIdentification of SH2B1β as a focal adhesion protein that regulates focal adhesion size and number.HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinomaIntegrin αIIbβ3 transmembrane domain separation mediates bi-directional signaling across the plasma membrane.New insights into vinculin function and regulation.The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties.Vinculin motion modes analysis with elastic network model.
P2860
Q24307815-3B34E91F-3A6E-4C0E-B031-527A313C3156Q24657852-212DF8F5-4C0A-41F5-AC2D-4BC3292E3321Q26765360-C3706A41-A167-4BC6-8141-26D88B281555Q27009352-324AEA0E-FCBC-4AA9-9460-63CA86C417ACQ27021287-332CEBB8-A562-4F32-B2C0-CF098D92BF72Q27339859-DEC6CA5A-4C74-4491-ACAD-1E73935E0C0EQ28248750-04C265D9-0C5C-44BC-A2DF-ACF503D72F50Q28263339-47B2BDC1-2026-40B4-90AF-16F5633719EDQ28386237-EDA6038C-AE7B-4B0B-8DBC-E55318FA4A0CQ28483856-D6DCEEB1-A06F-457B-86EF-55618244E55AQ28539896-5F4E98FE-B6BF-465C-BDF7-7C9E5255128DQ28566747-5FCCD5BB-A27B-4455-A086-DACD80478854Q28591795-1380EC7A-B347-4E4A-810F-0B698BA2C1ABQ28592273-C477052A-52FE-4154-8C02-0073FA8B9DE3Q30405334-8D6874C3-A4F8-4234-BCA7-0677E95A57DDQ30407809-6FD9F375-8534-4083-945E-C513C8E55241Q30441610-02C951FE-05CF-44B7-83EE-D4D0A4FC0623Q30577227-A9EBE6E4-3536-4F46-835B-FA3188C8A994Q30640795-8CE31CBB-83FE-4D6E-A48E-2230B643BE91Q30651113-0E83BFD5-8729-4892-970C-A82A4720AD53Q30841338-4879FE08-DAEE-4D43-9125-A8C2EF625A5DQ30854376-2DEEAF09-F644-45DC-B315-67E29868294CQ33642126-BDB6B0E1-1382-4471-B0AF-2BDCEF8F9BF9Q33644890-56454839-1C34-4D0B-AA17-2B9922925182Q33800219-B081DEA6-1ED9-4F1F-B8D2-8298D784A66BQ33904439-ED2C2B78-5BE9-438F-9B93-255C040F8F10Q34062219-2D95DFC0-0528-4C6E-B8C9-03F24CEACF0FQ34259083-C4CBB8B7-663C-414E-965F-88B386353247Q34500702-28B7F068-5BEF-4EA7-8187-E9B0029E2C5AQ34590952-3F20AE55-10BD-44A3-9394-BB59437BBF8BQ34718705-8AC94163-D9B3-43D8-A90B-0CB671F05DABQ35059908-BF53BAD9-AF0D-45EA-9179-88ABE1CB2F96Q35061682-0629DC5D-08AF-4217-A62B-42695234A22FQ35149147-E0AF9479-CFE6-4250-9487-5DE76B9C01FBQ35210820-CB787498-8799-48CA-8805-4F09F8F4947FQ35413993-B1A51B0D-D8FE-45FF-9FDE-CD216C4DA59EQ35548568-42983ABA-E4C0-4C34-A771-FCD2EF498E0FQ35591684-41307253-46DD-44F1-9EB8-27541D612C7FQ35639727-5C490312-6438-4CDD-8035-10A42C1CD82CQ35719280-CF839AE5-9099-4C66-8234-B0856D82F550
P2860
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Vinculin modulation of paxilli ...... control survival and motility.
@ast
Vinculin modulation of paxilli ...... control survival and motility.
@en
type
label
Vinculin modulation of paxilli ...... control survival and motility.
@ast
Vinculin modulation of paxilli ...... control survival and motility.
@en
prefLabel
Vinculin modulation of paxilli ...... control survival and motility.
@ast
Vinculin modulation of paxilli ...... control survival and motility.
@en
P2093
P2860
P356
P1476
Vinculin modulation of paxilli ...... control survival and motility
@en
P2093
Christopher E Turner
Eileen D Adamson
Klaus M Hahn
M Cecilia Subauste
Sachiko Junger
P2860
P304
P356
10.1083/JCB.200308011
P407
P577
2004-05-01T00:00:00Z