Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation.
about
Mechanics of T cell receptor gene rearrangementQuantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoireCentral tolerance: learning self-control in the thymusc-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xLA supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activationDetailed analysis of gene expression during development of T cell lineages in the thymus.Numerical modelling of the V-J combinations of the T cell receptor TRA/TRD locusTCR affinity for self-ligands influences the development and function of encephalitogenic T cells.Receptor selection in B and T lymphocytes.Revision of T cell receptor {alpha} chain genes is required for normal T lymphocyte development.The role of the thymus in tolerance.Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity.Receptor editing in lymphocyte development and central tolerance.PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.Thymic selection revisited: how essential is it?Role for rearranged variable gene segments in directing secondary T cell receptor alpha recombination.Tolerance-induced receptor selection: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection.Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus.Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombinationDefects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes.Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors.The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo.Positive selection of CD4(+) T cells is induced in vivo by agonist and inhibited by antagonist peptides.Predominant role of T cell receptor (TCR)-alpha chain in forming preimmune TCR repertoire revealed by clonal TCR reconstitution system.T cell receptor gene rearrangement lineage analysis reveals clues for the origin of highly restricted antigen-specific repertoiresRestricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection.Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes.Roadmap to a better therapeutic tumor vaccine.Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes.Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions.Molecular and genetic parameters defining T-cell clonal selection.Immune tolerance and transplantation.Nuclear transferred embryonic stem cells for analysis of B1 B-lymphocyte development.T-cell tolerance: central and peripheralStage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development.
P2860
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P2860
Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Rapid deletion of rearranged T ...... e T cell repertoire formation.
@ast
Rapid deletion of rearranged T ...... e T cell repertoire formation.
@en
type
label
Rapid deletion of rearranged T ...... e T cell repertoire formation.
@ast
Rapid deletion of rearranged T ...... e T cell repertoire formation.
@en
prefLabel
Rapid deletion of rearranged T ...... e T cell repertoire formation.
@ast
Rapid deletion of rearranged T ...... e T cell repertoire formation.
@en
P2860
P356
P1476
Rapid deletion of rearranged T ...... he T cell repertoire formation
@en
P2093
P2860
P304
11834-11839
P356
10.1073/PNAS.95.20.11834
P407
P577
1998-09-01T00:00:00Z