Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells.
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RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunctionMitochondria, calcium and cell death: a deadly triad in neurodegenerationAmyloidosis in Retinal Neurodegenerative DiseasesThe Rationale for Insulin Therapy in Alzheimer's DiseaseDrug Development in Alzheimer's Disease: The Contribution of PET and SPECTKilling Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's DiseaseAlterations in Mitochondrial Quality Control in Alzheimer's DiseaseNeuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathwaysA review on mitochondrial restorative mechanism of antioxidants in Alzheimer's disease and other neurological conditionsβ-Amyloid: the key peptide in the pathogenesis of Alzheimer's diseaseMolecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisalAlzheimer's pathogenesis and its link to the mitochondrionMitochondrial dysfunction: different routes to Alzheimer's disease therapyNuclear export of proteins and drug resistance in cancerOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseHIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidaseMitochondrial targeting of mouse NQO1 and CYP1B1 proteinsUnfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2ASGTA antagonizes BAG6-mediated protein triageMitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell deathA mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicineDual targeting of antioxidant and metabolic enzymes to the mitochondrion and the apicoplast of Toxoplasma gondiiMeta-analysis of the rs2075650 polymorphism and risk of Alzheimer disease.Pathogenesis of Alzheimer's diseaseCytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's diseaseMitochondria are related to synaptic pathology in Alzheimer's disease.Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive declineOverexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's diseaseInsights into the effects of alpha-synuclein expression and proteasome inhibition on glutathione metabolism through a dynamic in silico model of Parkinson's disease: validation by cell culture data.The efficiency of protein compartmentalization into the secretory pathway.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formationSignal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein.APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure.New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Multiple pathogenic proteins implicated in neuronopathic Gaucher disease miceSuperoxide anion, uncoupling proteins and Alzheimer's disease.Genetic variation at a single locus and age of onset for Alzheimer's disease.Convergence of amyloid-beta and tau pathologies on mitochondria in vivo.The Alzheimer's disease mitochondrial cascade hypothesis
P2860
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P2860
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Mitochondrial targeting and a ...... al function in neuronal cells.
@ast
Mitochondrial targeting and a ...... al function in neuronal cells.
@en
type
label
Mitochondrial targeting and a ...... al function in neuronal cells.
@ast
Mitochondrial targeting and a ...... al function in neuronal cells.
@en
prefLabel
Mitochondrial targeting and a ...... al function in neuronal cells.
@ast
Mitochondrial targeting and a ...... al function in neuronal cells.
@en
P2093
P2860
P921
P356
P1476
Mitochondrial targeting and a ...... al function in neuronal cells.
@en
P2093
Gopa Biswas
Hindupur K Anandatheerthavarada
Marie-Anne Robin
Narayan G Avadhani
P2860
P356
10.1083/JCB.200207030
P407
P577
2003-04-01T00:00:00Z