Dominant cataracts result from incongruous mixing of wild-type lens connexins.

Dominant cataracts result from incongruous mixing of wild-type lens connexins.

Item
http://www.wikidata.org/entity/Q36323542
Gap junction mediated intercellular metabolite transfer in the cochlea is compromised in connexin30 null miceMotifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensingConnexin 48.5 is required for normal cardiovascular function and lens development in zebrafish embryos.Gap junctions.Mutation of the gap junction protein alpha 8 (GJA8) gene causes autosomal recessive cataract.Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.Connexin 46 (cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleusLens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells.Lens gap junctions in growth, differentiation, and homeostasis.Connections between connexins, calcium, and cataracts in the lens.Gap junction communication influences intercellular protein distribution in the lens.Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis.Microphthalmia and cataract in rats with a novel point mutation in connexin 50 - L7Q.Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts.Identification and Functional Assessment of Age-Dependent Truncations to Cx46 and Cx50 in the Human Lens.The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium.
P2860

Dominant cataracts result from incongruous mixing of wild-type lens connexins.

Item
http://www.wikidata.org/entity/Q36323542
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@ast
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@en
type
label
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@ast
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@en
prefLabel
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@ast
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932