Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex
about
CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesisGRK2: multiple roles beyond G protein-coupled receptor desensitizationBeta-arrestins: multifunctional cellular mediatorsIntermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs)Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis.Genome-scale transcriptional analysis reveals key genes associated with the development of type II diabetes in mice.Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of beta-Adrenergic Receptors to Phosphoinositide 3-Kinase.Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanismLigand-directed signalling at beta-adrenoceptorsPituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survivalProlyl hydroxylase 2: a novel regulator of β2 -adrenoceptor internalization.Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signalingPI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.A-kinase anchoring proteins: scaffolding proteins in the heart.Protein translocation in photoreceptor light adaptation: a common theme in vertebrate and invertebrate vision.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsPI-loting membrane traffic.A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathwayBeta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins.Cancer Therapy Targeting the HER2-PI3K Pathway: Potential Impact on the Heart.G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling.IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism.Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibitionPhosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils.Adrenergic signaling and oxidative stress: a role for sirtuins?Proteomic identification of dengue virus binding proteins in Aedes aegypti mosquitoes and Aedes albopictus cells.Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt.The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targetsSpecific PI3K isoform modulation in heart failure: lessons from transgenic mice.Regulation of β-adrenergic receptor function: an emphasis on receptor resensitization.G-protein coupled receptor resensitization-appreciating the balancing act of receptor function.β-Arrestin-kinase scaffolds: turn them on or turn them off?Therapeutic applications of PI3K inhibitors in cardiovascular diseases.β-arrestins and G protein-coupled receptor trafficking.PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.
P2860
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P2860
Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex
description
2002 nî lūn-bûn
@nan
2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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name
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@ast
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@en
type
label
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@ast
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@en
prefLabel
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@ast
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@en
P2093
P2860
P356
P1476
Phosphoinositide 3-kinase regu ...... receptor/beta-arrestin complex
@en
P2093
Dean Chamberlain
Howard A Rockman
Larry Barak
Marc G Caron
Sathyamangla V Naga Prasad
Stéphane A Laporte
P2860
P304
P356
10.1083/JCB.200202113
P407
P577
2002-08-05T00:00:00Z