Understanding microtubule dynamics for improved cancer therapy.
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Brain endothelial cell-cell junctions: how to "open" the blood brain barrierMVL-PLA2, a snake venom phospholipase A2, inhibits angiogenesis through an increase in microtubule dynamics and disorganization of focal adhesionsMolecular alterations underlying the enhanced disruption of spermatogenesis by 2,5-hexanedione and carbendazim co-exposureMicrotubule regulation of corneal fibroblast morphology and mechanical activity in 3-D culture.Role of YY1 in the pathogenesis of prostate cancer and correlation with bioinformatic data sets of gene expressionTubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cellsSynthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.Tubulin proteomics: towards breaking the code.Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivoKIF2A silencing inhibits the proliferation and migration of breast cancer cells and correlates with unfavorable prognosis in breast cancer.Changes in gene expression and cellular architecture in an ovarian cancer progression model.Tubulin inhibitors: pharmacophore modeling, virtual screening and molecular docking.Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.Phosphorylation of α-tubulin by protein kinase C stimulates microtubule dynamics in human breast cellsAzaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.Biological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitorPredictive and prognostic values of Tau and BubR1 protein in prostate cancer and their relationship to the Gleason score.Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents.Photoinduced partial unfolding of tubulin bound to meso-tetrakis(sulfonatophenyl) porphyrin leads to inhibition of microtubule formation in vitro.Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivativesSynthesis and biological evaluation of imidazopyridine-oxindole conjugates as microtubule-targeting agents.Leaf Extracts of Calocedrus formosana (Florin) Induce G2/M Cell Cycle Arrest and Apoptosis in Human Bladder Cancer CellsConvergent synthesis and biological evaluation of 2-amino-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as microtubule targeting agents.Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.Microtubule stability studied by three-dimensional molecular theory of solvationHYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling PathwayClassifying ten types of major cancers based on reverse phase protein array profiles.One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors.The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo.BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9.New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.Expression of Nucleolin Affects Microtubule Dynamics.Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.Effects of Visible-Light Irradiation of Protoporphyrin IX on the Self-Assembly of Tubulin HeterodimersAnticancer activity of a novel small molecule tubulin inhibitor STK899704Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents.
P2860
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P2860
Understanding microtubule dynamics for improved cancer therapy.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Understanding microtubule dynamics for improved cancer therapy.
@ast
Understanding microtubule dynamics for improved cancer therapy.
@en
type
label
Understanding microtubule dynamics for improved cancer therapy.
@ast
Understanding microtubule dynamics for improved cancer therapy.
@en
prefLabel
Understanding microtubule dynamics for improved cancer therapy.
@ast
Understanding microtubule dynamics for improved cancer therapy.
@en
P1476
Understanding microtubule dynamics for improved cancer therapy
@en
P2093
P2888
P304
P356
10.1007/S00018-005-5330-X
P577
2005-12-01T00:00:00Z