Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
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Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality controlIn vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis.Sec3p is needed for the spatial regulation of secretion and for the inheritance of the cortical endoplasmic reticulum.Determinants of RING-E2 fidelity for Hrd1p, a membrane-anchored ubiquitin ligase.Shadows of an absent partner: ATP hydrolysis and phosphoenzyme turnover of the Spf1 (sensitivity to Pichia farinosa killer toxin) P5-ATPase.Different polarisome components play distinct roles in Slt2p-regulated cortical ER inheritance in Saccharomyces cerevisiae.Aux1p/Swa2p is required for cortical endoplasmic reticulum inheritance in Saccharomyces cerevisiae.Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11pINSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteinsThe Ca2+ homeostasis defects in a pgm2Delta strain of Saccharomyces cerevisiae are caused by excessive vacuolar Ca2+ uptake mediated by the Ca2+-ATPase Pmc1p.Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo.Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes.The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum.Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae.Manganese redistribution by calcium-stimulated vesicle trafficking bypasses the need for P-type ATPase function.7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndromeYeast genes controlling responses to topogenic signals in a model transmembrane protein.ER-resident proteins PDR2 and LPR1 mediate the developmental response of root meristems to phosphate availabilityEssential role of calcineurin in response to endoplasmic reticulum stress.Pollen development and fertilization in Arabidopsis is dependent on the MALE GAMETOGENESIS IMPAIRED ANTHERS gene encoding a type V P-type ATPase.Two distinctly localized p-type ATPases collaborate to maintain organelle homeostasis required for glycoprotein processing and quality controlCalcium release and influx in yeast: TRPC and VGCC rule another kingdom.HRD gene dependence of endoplasmic reticulum-associated degradationBioinformatic characterization of p-type ATPases encoded within the fully sequenced genomes of 26 eukaryotes.The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase isozyme Hmg2.Ca2+ induces spontaneous dephosphorylation of a novel P5A-type ATPase.The endoplasmic reticulum-associated degradation pathways of budding yeast.Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene.In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase.Geranylgeranyl pyrophosphate is a potent regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA reductase degradation in yeast.Inhibition of the Formation of the Spf1p Phosphoenzyme by Ca2.Computational approaches for classification and prediction of P-type ATPase substrate specificity in Arabidopsis.Lipid-mediated, reversible misfolding of a sterol-sensing domain protein.The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics.An oxysterol-derived positive signal for 3-hydroxy- 3-methylglutaryl-CoA reductase degradation in yeast.Structural control of endoplasmic reticulum-associated degradation: effect of chemical chaperones on 3-hydroxy-3-methylglutaryl-CoA reductase.Parkinson disease related ATP13A2 evolved early in animal evolution.
P2860
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P2860
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
description
2000 nî lūn-bûn
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2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
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2000年學術文章
@zh-hant
name
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@ast
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@en
type
label
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@ast
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@en
prefLabel
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@ast
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@en
P2093
P2860
P356
P1476
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p.
@en
P2093
P2860
P304
P356
10.1083/JCB.148.5.915
P407
P577
2000-03-01T00:00:00Z