MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation. - Wikidata - wikimedia - TriplyDB

MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.

MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.

http://www.wikidata.org/entity/Q36339939

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Non-coding RNAs in lung cancer MiR-92a mediates AZD6244 induced apoptosis and G1-phase arrest of lymphoma cells by targeting Bim Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494 MicroRNA expression as risk biomarker of breast cancer metastasis: a pilot retrospective case-cohort study.Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury.MicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cells The new concepts on overcoming drug resistance in lung cancer.Leishmania donovani resides in modified early endosomes by upregulating Rab5a expression via the downregulation of miR-494.miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT.Angiotensin II-regulated microRNA 483-3p directly targets multiple components of the renin-angiotensin system.Upregulation of microRNA135a-3p and death receptor 5 plays a critical role in Tanshinone I sensitized prostate cancer cells to TRAIL induced apoptosis.Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.MicroRNAs in Cancer Biology and Therapy: Current Status and Perspectives.MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells miR-503 represses human cell proliferation and directly targets the oncogene DDHD2 by non-canonical target pairing.Characterizing dynamic regulatory programs in mouse lung development and their potential association with tumourigenesis via miRNA-TF-mRNA circuits.Deleting maternal Gtl2 leads to growth enhancement and decreased expression of stem cell markers in teratoma MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells.MicroRNAs: short non-coding players in cancer chemoresistance.MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer Discriminating between Terminal- and Non-Terminal Respiratory Unit-Type Lung Adenocarcinoma Based on MicroRNA Profiles.A regulatory loop containing miR-26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells.Epigenetics and miRNA as predictive markers and targets for lung cancer chemotherapy.MicroRNA‑361‑5p suppresses cancer progression by targeting signal transducer and activator of transcription 6 in non‑small cell lung cancer BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs by targeting ten eleven translocation 1 in invasive human hepatocellular carcinoma tumors Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas.BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.Targeting survivin using a combination of miR‑494 and survivin shRNA has synergistic effects on the suppression of prostate cancer growth MiR-25 promotes hepatocellular carcinoma cell growth, migration and invasion by inhibiting RhoGDI1 Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.MiR-494 Inhibits Epithelial Ovarian Cancer Growth by Targeting c-Myc.MicroRNA Profiles of Barrett's Esophagus and Esophageal Adenocarcinoma: Differences in Glandular Non-native Epithelium.3,39-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B–Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells.Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2.MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC.miR-494 inhibits ovarian cancer cell proliferation and promotes apoptosis by targeting FGFR2.The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.MicroRNA-494 inhibits proliferation and metastasis of osteosarcoma through repressing insulin receptor substrate-1.Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis.

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MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.

http://www.wikidata.org/entity/Q36339939

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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type

label

MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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prefLabel

MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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Proceedings of the National Academy of Sciences of the United States of America

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MiR-494 is regulated by ERK1/2 ...... r through BIM down-regulation.

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Brad Bolon

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Ciro Zanca

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Gerolama Condorelli

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Gianpiero Di Leva

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Giulia Romano

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Luciano Cascione

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Mario Acunzo

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Michela Garofalo

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P2860

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation

Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action

The functions of animal microRNAs

MicroRNA signatures in human cancers

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

Characterization of PEA-15, a major substrate for protein kinase C in astrocytes

Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro

AP-1 as a regulator of cell life and death

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16570-16575

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10.1073/PNAS.1207917109

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41

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109

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Carlo Maria Croce

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2012-09-24T00:00:00Z

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231212134

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23012423

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apoptotic process

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3478630

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