Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models.
about
Inhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cellsGATA factor mutations in hematologic disease.The aurora kinases in cell cycle and leukemiaPrognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy.Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international studyControl of developmentally primed erythroid genes by combinatorial co-repressor actionsBaicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrestDNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in miceHh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene.Whole-exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia.Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7.An update on the pharmacokinetics and pharmacodynamics of alisertib, a selective Aurora kinase A inhibitor.miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cellsMN1-Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells.Molecular pathways: induction of polyploidy as a novel differentiation therapy for leukemia.DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia.Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study.Prognostic impact of specific molecular profiles in pediatric acute megakaryoblastic leukemia in non-Down syndrome.Clinical Courses of Two Pediatric Patients with Acute Megakaryoblastic Leukemia Harboring the CBFA2T3-GLIS2 Fusion GeneGLIS1-3: emerging roles in reprogramming, stem and progenitor cell differentiation and maintenance.Acute myeloid leukemiaTherapeutic targeting of Aurora A kinase in Philadelphia chromosome-positive ABL tyrosine kinase inhibitor-resistant cells
P2860
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P2860
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Characterization of novel geno ...... tic leukemia xenograft models.
@ast
Characterization of novel geno ...... tic leukemia xenograft models.
@en
type
label
Characterization of novel geno ...... tic leukemia xenograft models.
@ast
Characterization of novel geno ...... tic leukemia xenograft models.
@en
prefLabel
Characterization of novel geno ...... tic leukemia xenograft models.
@ast
Characterization of novel geno ...... tic leukemia xenograft models.
@en
P2093
P2860
P50
P356
P1476
Characterization of novel geno ...... tic leukemia xenograft models.
@en
P2093
Anne-Laure Bauchet
Bastien Gerby
Cathy Ignacimouttou
Clarisse Thiollier
Dirk Reinhardt
Françoise Pflumio
Isabelle Radford
Judith Landman-Parker
Justine Guégan
M'boyba Diop
P2860
P304
P356
10.1084/JEM.20121343
P407
P50
P577
2012-10-08T00:00:00Z