Structural studies on the murine Ia alloantigens. V. Evidence that the structural gene for the I-E/C beta polypeptide is encoded within the I-A subregion.
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Binding of purified, soluble major histocompatibility complex polypeptide chains onto isolated T-cell receptors. I. Reactivity against allo- and self-determinants.Demonstration of structural polymorphism among HLA-DR light chains by two-dimensional gel electrophoresis.Growth of SJL/J-derived transplantable reticulum cell sarcoma as related to its ability to induce T-cell proliferation in the host. I. Dominant negative genetic influences of other parent haplotype in F1 hybrids of SJL/J miceSerological and biochemical identification of hybrid Ia antigensGene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n.Aberrant Ae (E beta) Ia polypeptide chain in H-2g2 haplotype mice. Possible result of an intragenic recombination or mutation.Antigen-specific T cell clones restricted to unique F1 major histocompatibility complex determinants. Inhibition of proliferation with monoclonal anti-Ia antibodyExpression of hybrid Ia molecules on the cell surface of reticulum cell sarcomas that are undetectable on host SJL/J lymphocytes.Structure of murine Ia antigens. Two dimensional electrophoretic analyses and high pressure liquid chromatography tryptic peptide maps of products of the I-A and I-E subregions and of an associated invariant polypeptideImmune response gene function correlates with the expression of an Ia antigen. I. Preferential association of certain Ae and E alpha chains results in a quantitative deficiency in expression of an Ae:E alpha complex.Polymorphism of human B-cell alloantigens: evidence for three loci within the HLA system.I-E/I-C region-associated induction of murine gamma interferon by a haplotype-restricted polyclonal T-cell mitogen derived from Mycoplasma arthritidis.RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex.In vivo effects of antibodies to immune response gene products. II. Suppression of humoral immune responses with monoclonal anti-I-A is due to suppressor cells.Antigen-specific, proliferating T lymphocyte clones. Methodology, specificity, MHC restriction and alloreactivity.Murine T lymphocyte clones with distinct immunological functions.The genetic control of human Ia alloantigens: a three-loci model derived from the immunochemical analysis of 'supertypic' specificities.
P2860
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P2860
Structural studies on the murine Ia alloantigens. V. Evidence that the structural gene for the I-E/C beta polypeptide is encoded within the I-A subregion.
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1979 nî lūn-bûn
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1979年の論文
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1979年学术文章
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1979年学术文章
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1979年学术文章
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name
Structural studies on the muri ...... oded within the I-A subregion.
@ast
Structural studies on the muri ...... oded within the I-A subregion.
@en
type
label
Structural studies on the muri ...... oded within the I-A subregion.
@ast
Structural studies on the muri ...... oded within the I-A subregion.
@en
prefLabel
Structural studies on the muri ...... oded within the I-A subregion.
@ast
Structural studies on the muri ...... oded within the I-A subregion.
@en
P2093
P2860
P356
P1476
Structural studies on the muri ...... oded within the I-A subregion.
@en
P2093
P2860
P304
P356
10.1084/JEM.149.4.981
P407
P577
1979-04-01T00:00:00Z