Structure of murine Ia antigens. Two dimensional electrophoretic analyses and high pressure liquid chromatography tryptic peptide maps of products of the I-A and I-E subregions and of an associated invariant polypeptide
about
The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarityDirect demonstration of critical amino acid residues required for cytotoxic T-lymphocyte allorecognition of H-2 class I antigensThe invariant chain forms complexes with class II major histocompatibility complex molecules and antigenic peptides "in vivo".Translation and assembly of HLA-DR antigens in Xenopus oocytes injected with mRNA from a human B-cell line.Predominant role of amino-terminal sequences in dictating efficiency of class II major histocompatibility complex alpha beta dimer expression.Transferrin synthesis by inducer T lymphocytes.Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chains.Immune response gene function correlates with the expression of an Ia antigen. I. Preferential association of certain Ae and E alpha chains results in a quantitative deficiency in expression of an Ae:E alpha complex.T cell clones specific for hybrid I-A molecules. Discrimination with monoclonal anti-I-Ak antibodiesExpression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.Isolation of cDNA clones for the p33 invariant chain associated with HLA-DR antigens.Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment.Molecular characterization of novel H-2 class I molecules expressed by a C3H UV-induced fibrosarcoma.In vivo effects of antibodies to immune response gene products. II. Suppression of humoral immune responses with monoclonal anti-I-A is due to suppressor cells.HLA-DR antigens: structure, separation of subpopulations, gene cloning and function.Antigen presentation by MHC class II molecules.Structure of the murine Ia-associated invariant (Ii) chain as deduced from a cDNA clone.Role of the H-2 complex in induction of T helper cells in vivo. III. Contribution of the I-E subregion to restriction sites recognized by I-A/E-restricted T cells.Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion moleculesIn vitro analysis of allogeneic lymphocyte interaction. VII. I-A-restricted self-reactive and alloreactive helper components of allogeneic effect factor are distinct donor T cell-derived Ia-molecules that recognize Ia determinants on antigen-present
P2860
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P2860
Structure of murine Ia antigens. Two dimensional electrophoretic analyses and high pressure liquid chromatography tryptic peptide maps of products of the I-A and I-E subregions and of an associated invariant polypeptide
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh
1981年學術文章
@zh-hant
name
Structure of murine Ia antigen ...... sociated invariant polypeptide
@ast
Structure of murine Ia antigen ...... sociated invariant polypeptide
@en
type
label
Structure of murine Ia antigen ...... sociated invariant polypeptide
@ast
Structure of murine Ia antigen ...... sociated invariant polypeptide
@en
prefLabel
Structure of murine Ia antigen ...... sociated invariant polypeptide
@ast
Structure of murine Ia antigen ...... sociated invariant polypeptide
@en
P2093
P2860
P356
P1476
Structure of murine Ia antigen ...... sociated invariant polypeptide
@en
P2093
D B Murphy
H O McDevitt
J A Frelinger
M McMillan
P2860
P304
P356
10.1084/JEM.153.4.936
P407
P577
1981-04-01T00:00:00Z