Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin - Wikidata - wikimedia - TriplyDB

Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin

Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin

http://www.wikidata.org/entity/Q36345757

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Neutralizing tumor-promoting chronic inflammation: a magic bullet?Beneficial autoimmunity at body surfaces - immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer IL-13 from intraepithelial lymphocytes regulates tissue homeostasis and protects against carcinogenesis in the skin Moving towards personalised therapy in head and neck squamous cell carcinoma through analysis of next generation sequencing data.Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change.Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos.The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation Cell competition: winning out by losing notch Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis.Thymic stromal lymphopoietin (TSLP) inhibits human colon tumor growth by promoting apoptosis of tumor cells.Ligand-receptor dissociated expression explains high TSLP without prognostic impact in human primary head and neck squamous cell carcinoma.No evidence for TSLP pathway activity in human breast cancer The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development Cutaneous Notch signaling in health and disease.Genetically engineered mouse models of cancer reveal new insights about the antitumor immune response.Direct control of regulatory T cells by keratinocytes.Therapeutic modulation of Notch signalling--are we there yet?Heterogeneity and plasticity of epidermal stem cells.Modeling cutaneous squamous carcinoma development in the mouse Thymic stromal lymphopoietin and cancer.The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines.Thymic Stromal Lymphopoietin: To Cut a Long Story Short.AllergoOncology - the impact of allergy in oncology: EAACI position paper.The role of barrier genes in epidermal malignancy.Notch as a tumour suppressor.Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.Evaluation of thymic stromal lymphopoietin (TSLP) and its correlation with lymphatic metastasis in human gastric cancer.Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.Analysis of chromatin accessibility in human epidermis identifies putative barrier dysfunction-sensing enhancers.Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth.The dual nature of Notch in tissue homeostasis and carcinogenesis.Notch Signaling in Development, Tissue Homeostasis, and Disease.Thymic stromal lymphopoietin induction by skin irritation is independent of tumour necrosis factor-α, but supported by interleukin-1.Virtual screening for inhibitors of the human TSLP:TSLPR interaction.Langerhans Cells: Sensing the Environment in Health and Disease.Tumor-derived high-mobility group box 1 and thymic stromal lymphopoietin are involved in modulating dendritic cells to activate T regulatory cells in a mouse model.A tumor-myeloid cell axis, mediated via the cytokines IL-1α and TSLP, promotes the progression of breast cancer.Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin.Understanding allergy and cancer risk: what are the barriers?

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Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin

http://www.wikidata.org/entity/Q36345757

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Ahu Turkoz

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Laura J Yockey

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Mustafa Turkoz

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Raphael Kopan

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Shadmehr Demehri

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Sindhu Manivasagam

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P2860

Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma

The Hallmarks of Cancer

Hallmarks of Cancer: The Next Generation

Inflammation and cancer

The black box illuminated: signals and signaling

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity

Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis

Canonical notch signaling functions as a commitment switch in the epidermal lineage

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