The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
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Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 ComparisonCrystal Structure and Molecular Imaging of the Nav Channel 3 Subunit Indicates a Trimeric AssemblyA Review of the Human Sigma-1 Receptor Structure.The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems.Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligandsSigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5LabThe sigma-1 receptor: a regulator of cancer cell electrical plasticity?Structural domains underlying the activation of acid-sensing ion channel 2a.Involvement of ion channels and transporters in carcinoma angiogenesis and metastasis.Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines.Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain.Sigma 1 Receptor and Ion Channel Dynamics in Cancer.The σ-1 receptor interacts directly with GluN1 but not GluN2A in the GluN1/GluN2A NMDA receptor.The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis.A direct interaction between the sigma-1 receptor and the hERG voltage-gated K+ channel revealed by atomic force microscopy and homogeneous time-resolved fluorescence (HTRF®).Improved expression and purification of sigma 1 receptor fused to maltose binding protein by alteration of linker sequenceSolution NMR studies reveal the location of the second transmembrane domain of the human sigma-1 receptor.The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats.TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain.Sigma-1 Receptor and Neuronal Excitability.The Sigma-1 Receptor-A Therapeutic Target for the Treatment of ALS?Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases.Sigma-1 Receptor and Pain.Sigma-1 receptor: a new player in neuroprotection against chemotherapy-induced peripheral neuropathy.
P2860
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P2860
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
description
2012 nî lūn-bûn
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2012年の論文
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The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@ast
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@en
type
label
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@ast
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@en
prefLabel
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@ast
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@en
P2093
P2860
P356
P1476
The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.
@en
P2093
Andrew P Stewart
David Crottès
Dilshan Balasuriya
J Michael Edwardson
Olivier Soriani
P2860
P304
37021-37029
P356
10.1074/JBC.M112.382077
P407
P577
2012-09-05T00:00:00Z