Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome
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Structure of the human sialophorin (CD43) gene. Identification of features atypical of genes encoding integral membrane proteinsAmino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin)Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndromeCharacterization of cDNAs encoding human leukosialin and localization of the leukosialin gene to chromosome 16Altered Golgi localization of core 2 beta-1,6-N-acetylglucosaminyltransferase leads to decreased synthesis of branched O-glycansPurification of two glycoproteins expressing beta 1-6 branched Asn-linked oligosaccharides from metastatic tumour cellsCD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanismAssociation of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.Adhesion-related glycocalyx study: quantitative approach with imaging-spectrum in the energy filtering transmission electron microscope (EFTEM).Novel clearance mechanisms of platelets.Evidence implicating calpain (Ca(2+)-dependent neutral protease) in the destructive thrombocytopenia of the Wiskott-Aldrich syndrome.Wiskott Aldrich syndrome: an immunodeficiency syndrome not rare in Western Australia.Branched O-linked oligosaccharides ectopically expressed in transgenic mice reduce primary T-cell immune responsesDefective expression of T cell-associated glycoprotein in severe combined immunodeficiency.Molecular heterogeneity of a lymphocyte glycoprotein in immunodeficient patients.Disregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival.Mass spectrometry-based identification of the tumor antigen UN1 as the transmembrane CD43 sialoglycoproteinCD43 promotes cells transformation by preventing merlin-mediated contact inhibition of growthActivation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins.Germ-line mosaicism simulates genetic heterogeneity in Wiskott-Aldrich syndrome.Role of O-glycosylation and expression of CD43 and CD45 on the surfaces of effector T cells in human T cell leukemia virus type 1 cell-to-cell infectionLeukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation culturesSignaling through CD43 regulates CD4 T-cell traffickingT cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome.CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes.Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation.Human immunodeficiency virus type 1-infected individuals make autoantibodies that bind to CD43 on normal thymic lymphocytesA monoclonal antibody to sialophorin (CD43) induces homotypic adhesion and activation of human monocytes.Altered glycosylation of leukosialin, CD43, in HIV-1-infected cells of the CEM lineWiskott-Aldrich syndrome: a multidisciplinary diseaseIntracellular patterns of sialophorin expression define a new molecular classification of breast cancer and represent new targets for therapy.Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells.CD43 in the nucleus and cytoplasm of lung cancer is a potential therapeutic target.Surface proteins and glycoproteins of human leucocytes.Definition of the gene loci in X-linked immunodeficiencies.CD43 promotes cell growth and helps to evade FAS-mediated apoptosis in non-hematopoietic cancer cells lacking the tumor suppressors p53 or ARF.Overexpression of leukocyte marker CD43 causes activation of the tumor suppressor proteins p53 and ARF.Core 2-containing O-glycans on CD43 are preferentially expressed in the memory subset of human CD4 T cells.The sequence of rat leukosialin (W3/13 antigen) reveals a molecule with O-linked glycosylation of one third of its extracellular amino acids.Monoclonal antibodies to leucosialin (CD43) induce homotypic aggregation of the human mast cell line HMC-1: characterization of leucosialin on HMC-1 cells.
P2860
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P2860
Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome
description
1984 nî lūn-bûn
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1984年の論文
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1984年学术文章
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1984年学术文章
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1984年學術文章
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name
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@ast
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@en
type
label
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@ast
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@en
prefLabel
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@ast
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@en
P2093
P2860
P356
P1476
Characterization of a human ly ...... ve in Wiskott-Aldrich syndrome
@en
P2093
D M Kenney
E Remold-O'Donnell
P2860
P304
P356
10.1084/JEM.159.6.1705
P407
P577
1984-06-01T00:00:00Z