Parallel evolution of antibody variable regions by somatic processes: consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversi
about
Germ line variable regions that match hypermutated sequences in genes encoding murine anti-hapten antibodies.Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide.Different epitope structures select distinct mutant forms of an antibody variable region for expression during the immune response.Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.Molecular evolution of the human immunoglobulin E response: high incidence of shared mutations and clonal relatedness among epsilon VH5 transcripts from three unrelated patients with atopic dermatitisConceptual bases for quantifying the role of the environment on gene evolution: the participation of positive selection and neutral evolution.Oligonucleotide-directed mutagenesis of antibody combining sites.Gene Conversion-Like Events in the Diversification of Human Rearranged IGHV3-23*01 Gene Sequences.
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Q33960151-9AD34525-EF06-4C15-BDEB-129AB8AC4F1DQ35097270-BBFCCC5D-C9AA-4E26-A995-D2A9D2662B98Q36229997-16E2514E-1BC5-40AD-A27D-5A2C08897122Q36354162-EF233AC3-16BF-4B92-8776-7BA098D6C844Q36361154-4DD9F916-E522-45CA-8F89-48BB3F219154Q36974771-1132FD59-AC69-46B6-9015-68FC5C77E248Q38323037-82D5F95A-FD4D-4B1B-AA37-B42BF99C1A92Q42202201-244EE8BC-008B-47DD-B8B8-A6828ED76807
P2860
Parallel evolution of antibody variable regions by somatic processes: consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversi
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1990 nî lūn-bûn
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1990年の論文
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name
Parallel evolution of antibody ...... n rather than by gene conversi
@ast
Parallel evolution of antibody ...... n rather than by gene conversi
@en
type
label
Parallel evolution of antibody ...... n rather than by gene conversi
@ast
Parallel evolution of antibody ...... n rather than by gene conversi
@en
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Parallel evolution of antibody ...... n rather than by gene conversi
@ast
Parallel evolution of antibody ...... n rather than by gene conversi
@en
P2093
P2860
P356
P1476
Parallel evolution of antibody ...... n rather than by gene conversi
@en
P2093
L J Wysocki
M L Gefter
M N Margolies
P2860
P304
P356
10.1084/JEM.172.1.315
P407
P577
1990-07-01T00:00:00Z