Different epitope structures select distinct mutant forms of an antibody variable region for expression during the immune response.
about
Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigenDiversification of specificity after maturation of the antibody response to the HIV gp41 epitope ELDKWA.Antibodies that are specific for a single amino acid interchange in a protein epitope use structurally distinct variable regions.Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation.Random mutagenesis of two complementarity determining region amino acids yields an unexpectedly high frequency of antibodies with increased affinity for both cognate antigen and autoantigen.Oligonucleotide-directed mutagenesis of antibody combining sites.The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment.
P2860
Q31057169-D9A9BF73-3B33-4749-B8B5-955FE62DC778Q34163633-2E5A0E5C-0925-4823-8ED8-DD37E8D9CFE8Q36230382-97B1EB6F-4D3B-40CE-97AB-E4F05B0C72D8Q36364275-002A6387-38A6-4644-AEAB-6B0441ED70F6Q36365350-C408A961-2A78-460F-B524-5981EFDACDD8Q38323037-2EF0B0AE-3CF8-4730-B2B4-A168003C4C9CQ52039310-98908E5A-AAC0-4B6E-96B7-06FD4966CBFC
P2860
Different epitope structures select distinct mutant forms of an antibody variable region for expression during the immune response.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Different epitope structures s ...... on during the immune response.
@ast
Different epitope structures s ...... on during the immune response.
@en
type
label
Different epitope structures s ...... on during the immune response.
@ast
Different epitope structures s ...... on during the immune response.
@en
prefLabel
Different epitope structures s ...... on during the immune response.
@ast
Different epitope structures s ...... on during the immune response.
@en
P2093
P2860
P356
P1476
Different epitope structures s ...... on during the immune response.
@en
P2093
P2860
P304
P356
10.1084/JEM.173.3.665
P407
P577
1991-03-01T00:00:00Z