Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
about
Rapid cloning of high-affinity human monoclonal antibodies against influenza virusThe evolution within usTwo murine natural polyreactive autoantibodies are encoded by nonmutated germ-line genesAltered pattern of immunoglobulin hypermutation in mice deficient in Slip-GC proteinQuantifying evolutionary constraints on B-cell affinity maturationH3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccinationNucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system.Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigenImmunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.Influenza virus hemagglutinin-specific antibodies isolated from a combinatorial expression library are closely related to the immune response of the donor.Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.Identification of mutant monoclonal antibodies with increased antigen bindingSomatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 miceAn immunoglobulin mutator that targets G.C base pairs.Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis.The BALB/c mouse B-cell response to pigeon cytochrome c initiates as a heteroclitic response specific for the self antigen mouse cytochrome c.B-cell fate decisions following influenza virus infection.Antigen selection of anti-DSG1 autoantibodies during and before the onset of endemic pemphigus foliaceus.Nucleotide changes in sequential variants of influenza virus hemagglutinin genes and molecular structures of corresponding monoclonal antibodies specific for each variant.Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.Silent development of memory progenitor B cellsSomatic immunoglobulin hypermutation.Anti-DNA antibody production by CD5+ and CD5- B cells of patients with systemic lupus erythematosus.B-cell-lineage immunogen design in vaccine development with HIV-1 as a case studySignificant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.Protein evolution on rugged landscapes.Construction and expression of a recombinant antibody-targeted plasminogen activatorStructure and function of anti-DNA autoantibodies derived from a single autoimmune mouse.Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains.Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.Retention of an idiotypic determinant in a human B-cell lymphoma undergoing immunoglobulin variable-region mutationIn situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations.Selection of immunoglobulin variable regions in autoimmunity to DNA.Development of human antibody variable genes in systemic autoimmunity.Stochastic control of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice.Rearrangements of DNA mediated by terminal transferase.Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.Focused antibody response to influenza linked to antigenic drift
P2860
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P2860
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@ast
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@en
type
label
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@ast
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@en
prefLabel
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@ast
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@en
P2093
P2860
P356
P1476
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
@en
P2093
P2860
P304
P356
10.1084/JEM.161.4.687
P407
P577
1985-04-01T00:00:00Z