Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.
about
The structural basis of repertoire shift in an immune response to phosphocholineIdentification of mutant monoclonal antibodies with increased antigen bindingSomatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 miceExpression studies of catalytic antibodies.Apotosis of mature B cells.Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus.Covalent binding antibodies suppress advanced glycation: on the innate tier of adaptive immunity.Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.Characterization of gene use and efficacy of mouse monoclonal antibodies to Streptococcus pneumoniae serotype 8.Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice.Antibodies that are specific for a single amino acid interchange in a protein epitope use structurally distinct variable regions.Isolation and characterization of a light chain variable region gene for human rheumatoid factorsThe biologic significance of human natural autoimmune responses: relationship to the germline, early immune and malignant B cell variable gene repertoire.The molecular origin of anti-DNA antibodies.Anti-DNA antibodies, autoimmunity and the immunoglobulin repertoire.
P2860
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P2860
Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.
description
1987 nî lūn-bûn
@nan
1987 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Somatic diversification of S10 ...... s heavy chain variable region.
@ast
Somatic diversification of S10 ...... s heavy chain variable region.
@en
Somatic diversification of S10 ...... s heavy chain variable region.
@nl
type
label
Somatic diversification of S10 ...... s heavy chain variable region.
@ast
Somatic diversification of S10 ...... s heavy chain variable region.
@en
Somatic diversification of S10 ...... s heavy chain variable region.
@nl
prefLabel
Somatic diversification of S10 ...... s heavy chain variable region.
@ast
Somatic diversification of S10 ...... s heavy chain variable region.
@en
Somatic diversification of S10 ...... s heavy chain variable region.
@nl
P2093
P2860
P356
P1476
Somatic diversification of S10 ...... s heavy chain variable region.
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.9.2926
P407
P577
1987-05-01T00:00:00Z