The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters.
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Organization of variable region segments of the human immunoglobulin heavy chain: duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segmentsA deletion map of the human immunoglobulin heavy chain variable regionB cell receptor editing in tolerance and autoimmunityConservation of an immunoglobulin variable-region gene family indicates a specific, noncoding functionMolecular cloning of the primary IgH repertoire: a quantitative analysis of VH gene usage in adult miceStochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cellsPreferential rearrangement of V kappa 4 gene segments in pre-B cell lines.Receptor selection in B and T lymphocytes.Revising B cell receptorsFunctional activities and immunoglobulin variable regions of human and murine monoclonal antibodies specific for the P1.7 PorA protein loop of Neisseria meningitidisStructural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus.Linkage mapping of a mouse gene, iv, that controls left-right asymmetry of the heart and viscera.Early rearrangements of genes encoding murine immunoglobulin kappa chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus.The genomic organization of immunoglobulin VH genes in Xenopus laevis shows evidence for interspersion of familiesInterrelating B cell subpopulations and environmental regulation with the expression of three tiers of repertoire diversity.Expression of V gene families during ontogeny and establishment of B cell repertoire.Comparative expression of adult and fetal V gene repertoires.Differential expression of VH gene families in peripheral B cell repertoires of newborn or adult immunoglobulin H chain congenic miceBiased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice.Receptor editing in self-reactive bone marrow B cells.Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglobulin heavy chain diversity.Differentiation and characterization of B-cell precursors detected in the yolk sac and embryo body of embryos beginning at the 10- to 12-somite stage.The mouse immunoglobulin kappa light-chain genes are located in early- and late-replicating regions of chromosome 6.Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice.Receptor editing in self-reactive bone marrow B cells. The Journal of Experimental Medicine. 1993. 177: 1009-1020.The early expression of some human autoantibody-associated heavy chain variable region genes is controlled by specific regulatory elements.Autoantibodies and the fetal antibody repertoire.From human autoantibodies to the fetal antibody repertoire to B cell malignancy: it's a small world after all.Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment.Genomic organization of the mouse T cell receptor V alpha family.Human and mouse monoclonal antibodies to blood group A substance, which are nearly identical immunochemically, use radically different primary sequences.Biased reading frames of pre-existing DH--JH coding joints and preferential nucleotide insertions at VH--DJH signal joints of excision products of immunoglobulin heavy chain gene rearrangements.RAG-1 and RAG-2 are not sufficient to direct all phases of immunoglobulin gene rearrangement in pre-B-cell lines.Variable region usage in B cell deficient mice in a model of experimental herpes simplex virus retinitis.Structural analyses of human developmentally regulated Vh3 genes.Variable regions of two murine antibodies that bind the SLE associated 16/6 idiotype.
P2860
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P2860
The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
The organization of the mouse ...... on of VH gene family clusters.
@ast
The organization of the mouse ...... on of VH gene family clusters.
@en
type
label
The organization of the mouse ...... on of VH gene family clusters.
@ast
The organization of the mouse ...... on of VH gene family clusters.
@en
prefLabel
The organization of the mouse ...... on of VH gene family clusters.
@ast
The organization of the mouse ...... on of VH gene family clusters.
@en
P2093
P2860
P356
P1476
The organization of the mouse ...... on of VH gene family clusters.
@en
P2093
J J Mackle
P H Brodeur
P2860
P304
P356
10.1084/JEM.168.6.2261
P407
P577
1988-12-01T00:00:00Z