Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
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Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophilsIntegrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrinsTumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response.Suppressed expression of ICAM-1 and LFA-1 and abrogation of leukocyte collaboration after exposure of human mononuclear leukocytes to respiratory syncytial virus in vitro. Comparison with exposure to influenza virusSuppression of LFA-1 expression by spermine is associated with enhanced methylation of ITGAL, the LFA-1 promoter area.Increased polyamine intake inhibits age-associated alteration in global DNA methylation and 1,2-dimethylhydrazine-induced tumorigenesisThe mechanisms by which polyamines accelerate tumor spread.Cytokine secretion and adhesion molecule expression by granuloma T lymphocytes in Mycobacterium avium infectionTumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils.The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells.Direct and regulated interaction of integrin alphaEbeta7 with E-cadherin.Role for a glycan phosphoinositol anchor in Fc gamma receptor synergy.The combination of anti-B7 monoclonal antibody and cyclosporin A induces alloantigen-specific anergy during a primary mixed lymphocyte reaction.Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activationMultiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family.Cytokines in contextIntegrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction.Coexpression of intercellular adhesion molecule-1 and class I major histocompatibility complex antigens on hepatocyte membrane in chronic viral hepatitis.Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic miceCell type-specific integrin variants with alternative alpha chain cytoplasmic domains.Accessory cell signals involved in T-cell activation.Impairment of natural killer cell activity in Chlamydia trachomatis infected individuals.Integrin signalling and function in immune cells.The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.Analysis of cytotoxic activity of the CD4+ T lymphocytes generated by local immunotherapy.Activated peripheral lymphocytes with increased expression of cell adhesion molecules and cytotoxic markers are associated with dengue fever disease.A single amino acid in the cytoplasmic domain of the beta 2 integrin lymphocyte function-associated antigen-1 regulates avidity-dependent inside-out signaling.Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.CD50 (intercellular adhesion molecule 3) stimulation induces calcium mobilization and tyrosine phosphorylation through p59fyn and p56lck in Jurkat T cell line.Expression of CD44 on rheumatoid synovial fluid lymphocytes.Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus.Interaction of leukocyte integrins with ligand is necessary but not sufficient for function.Phorbol esters induce differentiation of U-937 human promonocytic cells in the absence of LFA-1/ICAM-1-mediated intercellular adhesion.Regulated expression and function of CD11c/CD18 integrin on human B lymphocytes. Relation between attachment to fibrinogen and triggering of proliferation through CD11c/CD18.Regulated Ca2+ signalling through leukocyte CD11b/CD18 integrinIntegrin-mediated ras-extracellular regulated kinase (ERK) signaling regulates interferon gamma production in human natural killer cells.Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.An alternative leukocyte homotypic adhesion mechanism, LFA-1/ICAM-1-independent, triggered through the human VLA-4 integrin.Activation of beta(1) integrins mediates proliferation and inhibits apoptosis of intestinal CD4-positive lymphocytes.
P2860
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P2860
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@ast
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@en
type
label
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@ast
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@en
prefLabel
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@ast
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@en
P2093
P2860
P356
P1476
Leukocyte function-associated antigen 1 is an activation molecule for human T cells.
@en
P2093
M C Wacholtz
P E Lipsky
P2860
P304
P356
10.1084/JEM.170.2.431
P407
P577
1989-08-01T00:00:00Z