Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells
about
Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation sitep56Lck anchors CD4 to distinct microdomains on microvilli.The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen doseMolecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5Two-photon tissue imaging: seeing the immune system in a fresh light.Regulated movement of CD4 in and out of the immunological synapseClass II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 moleculeA single antigen-specific B cell can conjugate to either a type 1 or a type 2 helper T cellCD4-T-cell antigen receptor complexes on human leukemia T cells.Molecular dynamics in the membranes of helper T cells.CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodiesThe MHC class II ligand lymphocyte activation gene-3 is co-distributed with CD8 and CD3-TCR molecules after their engagement by mAb or peptide-MHC class I complexes.CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.Cross-linking of CD4 in a TCR/CD3-juxtaposed inhibitory state: a pFRET studyCD4 and CD8 molecules can physically associate with the same T-cell receptor.Imaging T-cell antigen recognition and comparing immunological and neuronal synapses.MyD88 deficiency leads to decreased NK cell gamma interferon production and T cell recruitment during Chlamydia muridarum genital tract infection, but a predominant Th1 response and enhanced monocytic inflammation are associated with infection resolHuman immunodeficiency virus type 1 gp120 mimics a hidden monomorphic epitope borne by class I major histocompatibility complex heavy chains.Repression of human immunodeficiency virus type 1 long terminal repeat-driven gene expression by binding of the virus to its primary cellular receptor, the CD4 molecule.Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity.Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events.The Lyt-2 molecule recognizes residues in the class I alpha 3 domain in allogeneic cytotoxic T cell responses.Leukocyte function-associated antigen 1 is an activation molecule for human T cells.Delayed thymocyte development induced by augmented expression of p56lck.Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions.Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor.The protein tyrosine kinase p56lck regulates cell adhesion mediated by CD4 and major histocompatibility complex class II proteins.Selective induction of apoptosis in mature T lymphocytes by variant T cell receptor ligands.Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling.Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex bindingThe human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.Type I interferon signaling exacerbates Chlamydia muridarum genital infection in a murine model.T-cell activation through immunological synapses and kinapses.Human immunodeficiency virus gp120 binding C'C" ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules.Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells.Shine a light: imaging the immune system.Co-receptors and recognition of self at the immunological synapse.Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule.Role of interaction of CD2 molecules with lymphocyte function-associated antigen 3 in T-cell recognition of nominal antigen.
P2860
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P2860
Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells
description
1987 nî lūn-bûn
@nan
1987 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@ast
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@en
Coclustering of CD4
@nl
type
label
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@ast
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@en
Coclustering of CD4
@nl
prefLabel
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@ast
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@en
Coclustering of CD4
@nl
P2093
P2860
P356
P1476
Coclustering of CD4 (L3T4) mol ...... s and antigen-presenting cells
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.16.5888
P407
P577
1987-08-01T00:00:00Z