Equivalence of human and mouse CD4 in enhancing antigen responses by a mouse class II-restricted T cell hybridoma.
about
Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC moleculeSpecies specificity and augmentation of responses to class II major histocompatibility complex molecules in human CD4 transgenic mice.Xenogeneic proliferation and lymphokine production are dependent on CD4+ helper T cells and self antigen-presenting cells in the mouse.CD4-mediated enhancement or inhibition of T cell activation does not require the CD4:p56lck associationThe two membrane proximal domains of CD4 interact with the T cell receptor.Coreceptor function of mutant human CD4 molecules without affinity to gp120 of human immunodeficiency virus.Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.Human CD4 restores normal T cell development and function in mice deficient in murine CD4.Species-specific binding of CD4 to the beta 2 domain of major histocompatibility complex class II molecules.HLA class II transgenic mice: the chance to unravel the basis of HLA class II associations with disease.T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.Preclinical development of keliximab, a Primatized anti-CD4 monoclonal antibody, in human CD4 transgenic mice: characterization of the model and safety studies.
P2860
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P2860
Equivalence of human and mouse CD4 in enhancing antigen responses by a mouse class II-restricted T cell hybridoma.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@ast
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@en
type
label
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@ast
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@en
prefLabel
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@ast
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@en
P2093
P2860
P356
P1476
Equivalence of human and mouse ...... I-restricted T cell hybridoma.
@en
P2093
B Tourvieille
J R Parnes
M C Miceli
M Schilham
P von Hoegen
P2860
P304
P356
10.1084/JEM.170.6.1879
P407
P577
1989-12-01T00:00:00Z