A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.
about
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activityEvidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein VPolymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cellsLymphotoxin-beta receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor kappaBCrystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzymeFurin-mediated processing of Pro-C-type natriuretic peptideAutolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activityIdentification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteasesADAMTS-1 protein anchors at the extracellular matrix through the thrombospondin type I motifs and its spacing regionA functional soluble form of the murine mannose receptor is produced by macrophages in vitro and is present in mouse serumSecretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunitsIdentification of key processes that control tumor necrosis factor availability in a tuberculosis granulomaThe Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity.Proteinases are isoform-specific regulators of the binding of transforming growth factor beta to alpha 2-macroglobulin.TLR4-dependent lipopolysaccharide-induced shedding of tumor necrosis factor receptors in mouse bone marrow granulocytes.Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion.The plasmin cascade and matrix metalloproteinases in non-small cell lung cancerEnhanced potency of the metalloprotease inhibitor TAPI-2 by multivalent displayAnti-TNF antibody treatment of Crohn's disease.Differential effects of total and partial neutralization of tumor necrosis factor on cell-mediated immunity to Mycobacterium bovis BCG infection.Human CD6 Down-Modulation following T-Cell Activation Compromises Lymphocyte Survival and Proliferative Responses.The soluble CD40 ligand sCD154 in systemic lupus erythematosusFull-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathwayLack of tumor necrosis factor alpha induces impaired proliferation of hepatitis B virus-specific cytotoxic T lymphocytes.Transmodulation of cell surface regulatory molecules via ectodomain shedding.Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression.Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities.Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injuryRegulation of matrix metalloproteinases and their inhibitor genes in lipopolysaccharide-induced endotoxemia in mice.Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability.NF-κB Signaling Dynamics Play a Key Role in Infection Control in Tuberculosis.Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF).Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses.Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent.Metalloproteinase-mediated release of human Fas ligandShedding of TNF receptor 2 by effector CD8⁺ T cells by ADAM17 is important for regulating TNF-α availability during influenza infection.Cytokine secretion requires phosphatidylcholine synthesisCleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases.
P2860
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P2860
A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@ast
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@en
type
label
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@ast
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@en
prefLabel
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@ast
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@en
P2093
P2860
P356
P1476
A metalloprotease inhibitor bl ...... F processing in T lymphocytes.
@en
P2093
B N Walter
C Otten-Evans
K M Mohler
P2860
P304
P356
10.1084/JEM.181.3.1205
P407
P577
1995-03-01T00:00:00Z