Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2.

Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2.

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http://www.wikidata.org/entity/Q36368633
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.The Goldilocks model for TCR-too much attraction might not be best for vaccine designTCR affinity for self-ligands influences the development and function of encephalitogenic T cells.Review article: molecular signals and genetic reprogramming in peripheral T-cell differentiation.Functional plasticity of an antigen-specific memory CD4 T cell population.Surface expression of MPT64 as a fusion with the PE domain of PE_PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in miceIdentification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells.Dose-dependent induction of murine Th1/Th2 responses to sheep red blood cells occurs in two steps: antigen presentation during second encounter is decisive.Characterization of antigenic variants of hepatitis C virus in immune evasion.Lipopolysaccharide-activated dendritic cells: "exhausted" or alert and waiting?Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection.Antigen-specific T helper cell function: differential cytokine expression in primary and memory responses.Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.Annexin-A1: a pivotal regulator of the innate and adaptive immune systems.The function of follicular helper T cells is regulated by the strength of T cell antigen receptor bindingAnalysis of lymphocytes in patients with Plasmodium vivax malaria and its relation to the annexin-A1 and IL-10.
P2860

Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2.

Item
http://www.wikidata.org/entity/Q36368633
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Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@ast
Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@en
type
label
Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@ast
Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@en
prefLabel
Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@ast
Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Alteration at a single amino a ...... lper cell type 1 (Th1) to Th2.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932