Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.
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Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.Respiratory syncytial virus infection sensitizes cells to apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligandApoptosis: role in myeloid cell developmentPathological survivin expression links viral infections with pathogenesis of erosive rheumatoid arthritisStabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTPFas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammationThe role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survivalRole of H2-calponin in regulating macrophage motility and phagocytosisThe PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis.The role of macrophage polarization in infectious and inflammatory diseasesAmniotic membrane induces apoptosis of interferon-gamma activated macrophages in vitro.Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors.The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages.Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearanceTranscriptional diversity during monocyte to macrophage differentiation.Macrophage Apoptosis and Efferocytosis in the Pathogenesis of AtherosclerosisA cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.The androgen receptor mediates antiapoptotic function in myometrial cellsSilencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cellsHeparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice.Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniaeMacrophage Mal1 deficiency suppresses atherosclerosis in low-density lipoprotein receptor-null mice by activating peroxisome proliferator-activated receptor-γ-regulated genes.ELK4 neutralization sensitizes glioblastoma to apoptosis through downregulation of the anti-apoptotic protein Mcl-1The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophagesRapid turnover of mcl-1 couples translation to cell survival and apoptosis.The antiapoptotic protein Mcl-1 controls the type of cell death in Theiler's virus-infected BHK-21 cells.TRAIL-mediated apoptosis in HIV-1-infected macrophages is dependent on the inhibition of Akt-1 phosphorylationNurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alphaPhosphatidylinositol-3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis.Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis.Glucose-6-phosphatase-β, implicated in a congenital neutropenia syndrome, is essential for macrophage energy homeostasis and functionality.Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner.Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null miceImbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.Redox regulation of PI 3-kinase signalling via inactivation of PTENGlycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritisMultiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.Regulation of phagocyte lifespan in the lung during bacterial infection.
P2860
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P2860
Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Constitutively activated Akt-1 ...... B, Bad, or caspase activation.
@ast
Constitutively activated Akt-1 ...... B, Bad, or caspase activation.
@en
type
label
Constitutively activated Akt-1 ...... B, Bad, or caspase activation.
@ast
Constitutively activated Akt-1 ...... B, Bad, or caspase activation.
@en
prefLabel
Constitutively activated Akt-1 ...... B, Bad, or caspase activation.
@ast
Constitutively activated Akt-1 ...... B, Bad, or caspase activation.
@en
P2093
P2860
P356
P1476
Constitutively activated Akt-1 ...... aB, Bad, or caspase activation
@en
P2093
P2860
P304
P356
10.1084/JEM.194.2.113
P407
P577
2001-07-01T00:00:00Z