High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.

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http://www.wikidata.org/entity/Q36369721
Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System.Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.Engineering of cell membrane to enhance heterologous production of hyaluronic acid in Bacillus subtilis.Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing.Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes.CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.While it is not deliberate, much of today's biomedical research contains logical and technical flaws, showing a need for corrective action.Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep.Global pairwise RNA interaction landscapes reveal core features of protein recognition.Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited GoatsCRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parametersFilamentation and restoration of normal growth in Escherichia coli using a combined CRISPRi sgRNA/antisense RNA approachComprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profiling
P2860

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.

Item
http://www.wikidata.org/entity/Q36369721
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2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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2017年學術文章
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2017年學術文章
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name
High-throughput biochemical pr ...... -target binding and unbinding.
@ast
High-throughput biochemical pr ...... -target binding and unbinding.
@en
type
label
High-throughput biochemical pr ...... -target binding and unbinding.
@ast
High-throughput biochemical pr ...... -target binding and unbinding.
@en
prefLabel
High-throughput biochemical pr ...... -target binding and unbinding.
@ast
High-throughput biochemical pr ...... -target binding and unbinding.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
High-throughput biochemical pr ...... -target binding and unbinding.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932