Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development
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Phenotypically distinct B cell development pathways map to the three B cell lineages in the mouseNatural Antibodies as Rheostats for Susceptibility to Chronic Diseases in the AgedHumanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Nutritionally mediated programming of the developing immune systemSiglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activationProgenitor cell origin plays a role in fate choices of mature B cellsKiller B lymphocytes: the evidence and the potential.Central B-cell tolerance: where selection begins.Receptor editing in lymphocyte development and central tolerance.In situ IgM production and clonal expansion of B-1 cells in peritoneal cavity promote elimination of C. albicans infection in IgH transgenic mice with VH derived from a natural antibody.Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrowNatural anti-intestinal goblet cell autoantibody production from marginal zone B cells.Human B-1 cells take the stage.Selection during development of VH11+ B cells: a model for natural autoantibody-producing CD5+ B cells.Peripheral B-cell maturation: the intersection of selection and homeostasis.B-cell homeostasis: digital survival or analog growth?Alternative routes to maturity: branch points and pathways for generating follicular and marginal zone B cells.IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools.Autoreactive B-1 B cells: constraints on natural autoantibody B cell antigen receptorsFetal Lymphoid Progenitors Become Restricted to B-1 Fates Coincident with IL-7Rα Expression.Immune response to lipoproteins in atherosclerosis.The cellular location of self-antigen determines the positive and negative selection of autoreactive B cellsThe broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies.Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues.Expression of plasma cell alloantigen 1 defines layered development of B-1a B-cell subsets with distinct innate-like functions.Peripheral blood CD5-positive B lymphocytes (B-1a cells) after allogeneic stem cell transplantation for acute myeloid leukaemia in humans.Oxidation-specific epitopes are important targets of innate immunity.Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma.Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression.Natural autoantibodies and associated B cells in immunity and autoimmunity.B cells generated by B-1 development can progress to chronic lymphocytic leukemia.A developmental switch between fetal and adult B lymphopoiesis.Perspectives on fetal derived CD5+ B1 B cellsA Hard(y) Look at B-1 Cell Development and Function.Tonic Signals: Why Do Lymphocytes Bother?B cell receptor signal strength determines B cell fate.NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome.Linking autoimmunity to the origin of the adaptive immune system.Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells.Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.
P2860
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P2860
Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Positive selection of anti-thy ...... bone marrow B cell development
@ast
Positive selection of anti-thy ...... bone marrow B cell development
@en
type
label
Positive selection of anti-thy ...... bone marrow B cell development
@ast
Positive selection of anti-thy ...... bone marrow B cell development
@en
prefLabel
Positive selection of anti-thy ...... bone marrow B cell development
@ast
Positive selection of anti-thy ...... bone marrow B cell development
@en
P2093
P2860
P356
P1476
Positive selection of anti-thy ...... bone marrow B cell development
@en
P2093
Joni Dashoff
Kyoko Hayakawa
Li-Jun Wen
Masanao Asano
Richard R Hardy
Susan A Shinton
P2860
P356
10.1084/JEM.20021459
P407
P577
2003-01-01T00:00:00Z