B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.
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The riddle of the dual expression of IgM and IgDAnergic B Cells: Precarious On-Call Warriors at the Nexus of Autoimmunity and False-Flagged PathogensRNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescenceThe chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cellsATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytesImmune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation.Partial tolerance of autoreactive B and T cells to erythrocyte-specific self-antigens in mice.Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses.ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production.Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development.Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.Divergence of primary cognate B- and T-cell proliferative responses to subcutaneous and intravenous immunization with virus-like particlesSelf DNA from lymphocytes that have undergone activation-induced cell death enhances murine B cell proliferation and antibody production.Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivoFOXO1 transcription factor: a critical effector of the PI3K-AKT axis in B-cell development.Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrowB cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cellsEstablishment of murine gammaherpesvirus latency in B cells is not a stochastic event.Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.B-cell homeostasis: digital survival or analog growth?A tolerogenic role for Toll-like receptor 9 is revealed by B-cell interaction with DNA complexes expressed on apoptotic cellsReversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes.Macrophages prevent the differentiation of autoreactive B cells by secreting CD40 ligand and interleukin-6The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.Regulation and Maintenance of an Adoptive T-Cell Dependent Memory B Cell Pool.Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.High affinity germinal center B cells are actively selected into the plasma cell compartment.Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation.Targeting Anti-Insulin B Cell Receptors Improves Receptor Editing in Type 1 Diabetes-Prone Mice.Virus-like display of a neo-self antigen reverses B cell anergy in a B cell receptor transgenic mouse model.Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodiesB cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivoA novel polymorphism of the human CD40 receptor with enhanced function.Sublingual injection of microparticles containing glycolipid ligands for NKT cells and subunit vaccines induces antibody responses in oral cavity.Visualizing the effects of antigen affinity on T-dependent B-cell differentiation.Unlinked memory helper responses promote long-lasting humoral alloimmunity.
P2860
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P2860
B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
B cell receptor-independent st ...... anergic self-reactive B cells.
@ast
B cell receptor-independent st ...... anergic self-reactive B cells.
@en
type
label
B cell receptor-independent st ...... anergic self-reactive B cells.
@ast
B cell receptor-independent st ...... anergic self-reactive B cells.
@en
prefLabel
B cell receptor-independent st ...... anergic self-reactive B cells.
@ast
B cell receptor-independent st ...... anergic self-reactive B cells.
@en
P2093
P2860
P356
P1476
B cell receptor-independent st ...... anergic self-reactive B cells
@en
P2093
Antony Basten
Jeffrey Crosbie
Jhagvaral Hasbold
Michelle Amesbury
Robert Brink
Sandra Gardam
P2860
P304
P356
10.1084/JEM.20022144
P407
P577
2003-03-31T00:00:00Z