Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
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Virus entry, assembly, budding, and membrane raftsEarly steps of retrovirus replicative cycleLipids and membrane microdomains in HIV-1 replicationActivation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomainsCholesterol promotes hemifusion and pore widening in membrane fusion induced by influenza hemagglutinin.CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surfaceMurine coronavirus requires lipid rafts for virus entry and cell-cell fusion but not for virus release.An envelope-determined, pH-independent endocytic route of viral entry determines the susceptibility of human immunodeficiency virus type 1 (HIV-1) and HIV-2 to Lv2 restriction.Modulation of entry of enveloped viruses by cholesterol and sphingolipids (Review).Viral entry, lipid rafts and caveosomes.The Role of Lipids in Retrovirus Replication.A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5.Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.Cytoplasmic body component TRIM5{alpha} requires lipid-enriched microdomains for efficient HIV-1 restriction.The roles of membrane microdomains (rafts) in T cell activation.Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5.The trinity of the cortical actin in the initiation of HIV-1 infectionCCR5 expression influences the progression of human breast cancer in a p53-dependent mannerStatins inhibit HIV-1 infection by down-regulating Rho activity.Requirements for CEACAMs and cholesterol during murine coronavirus cell entry.CXCR4-tropic, but not CCR5-tropic, human immunodeficiency virus infection is inhibited by the lipid raft-associated factors, acyclic retinoid analogs, and cholera toxin B subunit.Presence of host ICAM-1 in human immunodeficiency virus type 1 virions increases productive infection of CD4+ T lymphocytes by favoring cytosolic delivery of viral materialRetroviral proteins that interact with the host cell cytoskeletonViral attachment induces rapid recruitment of an innate immune sensor (TRIM5α) to the plasma membrane.Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trialProtein acylation and localization in T cell signaling (Review).Ceramide, a target for antiretroviral therapy.Roles for biological membranes in regulating human immunodeficiency virus replication and progress in the development of HIV therapeutics that target lipid metabolism.CD4 receptor localized to non-raft membrane microdomains supports HIV-1 entry. Identification of a novel raft localization marker in CD4.CD4 and CCR5 constitutively interact at the plasma membrane of living cells: a confocal fluorescence resonance energy transfer-based approach.Cellular membrane cholesterol is required for porcine reproductive and respiratory syndrome virus entry and release in MARC-145 cells.Mobility of the human immunodeficiency virus (HIV) receptor CD4 and coreceptor CCR5 in living cells: implications for HIV fusion and entry eventsHuman immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains.Filamin-A regulates actin-dependent clustering of HIV receptors.Human immunodeficiency virus type 1 enters primary human brain microvascular endothelial cells by a mechanism involving cell surface proteoglycans independent of lipid rafts.The role of lipid rafts in cancer cell adhesion and migration.The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface.Retrovirus infection strongly enhances scrapie infectivity release in cell culture.
P2860
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P2860
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@ast
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@en
type
label
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@ast
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@en
prefLabel
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@ast
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@en
P2093
P2860
P356
P1476
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.
@en
P2093
Ana C Carrera
Carlos Martínez-A
Concepción Gómez-Moutón
Emilia Mira
Gustavo Del Real
Pilar Lucas
Rosa Ana Lacalle
Santos Mañes
Sonia Jiménez-Baranda
P2860
P304
P356
10.1084/JEM.20020308
P407
P577
2002-08-01T00:00:00Z