Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production - Wikidata - wikimedia - TriplyDB

Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

http://www.wikidata.org/entity/Q36370908

about

miR-346 controls release of TNF-α protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling MicroRNAs: new regulators of Toll-like receptor signalling pathways Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk Association of Lyn kinase with membrane rafts determines its negative influence on LPS-induced signaling Gene expression in cortex and hippocampus during acute pneumococcal meningitis Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats BTK inhibitors in chronic lymphocytic leukemia: a glimpse to the future.TLR signaling and effector functions are intact in XLA neutrophils.Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3.Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response Molecular mechanisms that influence the macrophage m1-m2 polarization balance.Prospects for the development of small molecular weight compounds to replace anti-tumour necrosis factor biological agents.Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells B-cell homeostasis: digital survival or analog growth?The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib Toll-like receptor 4-, 7-, and 8-activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines.Toll-like receptor function in primary B cell defects.Toll-like receptor signaling in primary immune deficiencies.Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcγ Receptor (FcγR) Function.Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis.Clinical potential of targeting Bruton's tyrosine kinase.Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease MicroRNAs in the regulation of TLR and RIG-I pathways.Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.Tec family kinases: regulation of FcεRI-mediated mast-cell activation.Tec family kinases in inflammation and disease.Bruton tyrosine kinase (BTK) and its role in B-cell malignancy.MicroRNAs in rheumatoid arthritis: potential role in diagnosis and therapy.TLR signaling in mast cells: common and unique features.Bruton's tyrosine kinase--an integral protein of B cell development that also has an essential role in the innate immune system.The Complement Anaphylatoxins C5a and C3a Suppress IFN-β Production in Response to Listeria monocytogenes by Inhibition of the Cyclic Dinucleotide-Activated Cytosolic Surveillance Pathway.Roles of Non-coding RNAs in Respiratory Syncytial Virus (RSV) Infection.TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia.Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.Naturally occurring Bruton's tyrosine kinase mutations have no dominant negative effect in an X-linked agammaglobulinaemia cellular model.

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P2860

Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

http://www.wikidata.org/entity/Q36370908

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-sg

2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Bruton's tyrosine kinase is re ...... crosis factor alpha production

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Bruton's tyrosine kinase is re ...... crosis factor alpha production

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type

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Bruton's tyrosine kinase is re ...... crosis factor alpha production

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Bruton's tyrosine kinase is re ...... crosis factor alpha production

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Bruton's tyrosine kinase is re ...... crosis factor alpha production

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P1433

Journal of Experimental Medicine

P1476

Bruton's tyrosine kinase is re ...... crosis factor alpha production

@en

P2093

Brian M J Foxwell

http://www.w3.org/2001/XMLSchema#string

David Webster

http://www.w3.org/2001/XMLSchema#string

Fionula M Brennan

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Hiroyuki Mano

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Jamie Campbell

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John P McDaid

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Tara Mahon

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P2860

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

A simplified system for generating recombinant adenoviruses

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

BTK, the tyrosine kinase affected in X-linked agammaglobulinemia.

Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14.

Tec kinase pathways in lymphocyte development and transformation.

Beyond calcium: new signaling pathways for Tec family kinases.

Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent.

Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators.

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1603-1611

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scholarly article

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10.1084/JEM.20021845

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P433

12

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197

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Nicole J Horwood

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2003-06-01T00:00:00Z

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P5875

6966669

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12810683

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P921

lipopolysaccharide

P932

2193950

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