Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model.
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Central role of defective interleukin-2 production in the triggering of islet autoimmune destructionInterleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1Human leukocyte Antigen-DM polymorphisms in autoimmune diseasesThe Role of the Immune Response in Chlamydia trachomatis Infection of the Male Genital Tract: A Double-Edged SwordTreatment of autoimmune diabetes by inhibiting the initial eventA novel CD93 polymorphism in non-obese diabetic (NOD) and NZB/W F1 mice is linked to a CD4+ iNKT cell deficient stateGenetics, pathogenesis and clinical interventions in type 1 diabetesApoptosis of NOD.H2 h4 thyrocytes by low concentrations of iodide is associated with impaired control of oxidative stressWhere CD4+CD25+ T reg cells impinge on autoimmune diabetesHow dying cells alert the immune system to dangerThe role of dendritic cells in autoimmunityResolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC moleculesReal-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance.An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and functionRIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.Making antigen invisible: a coinhibitory molecule regulates the interaction between T cells and dendritic cells.Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damageTargeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence.The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach.The central role of antigen presentation in islets of Langerhans in autoimmune diabetesCathepsin L is essential for onset of autoimmune diabetes in NOD mice.Role of innate immunity in the pathogenesis of type 1 and type 2 diabetes.Cutting edge: merocytic dendritic cells break T cell tolerance to beta cell antigens in nonobese diabetic mouse diabetes.Alpha4beta7 integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic miceThe role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturationMacrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetesMicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunityEndocrine self and gut non-self intersect in the pancreatic lymph nodesCongenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes.Membrane repair and immunological danger.Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues.Annexin A1 on the surface of early apoptotic cells suppresses CD8+ T cell immunity.The inflammatory response to cell death.Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humansA missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific mannerRole of innate immunity in diabetes and metabolism: recent progress in the study of inflammasomes.CCR7 directs the recruitment of T cells into inflamed pancreatic islets of nonobese diabetic (NOD) mice.Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases
P2860
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P2860
Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Physiological beta cell death ...... ls in a type-1 diabetes model.
@ast
Physiological beta cell death ...... ls in a type-1 diabetes model.
@en
type
label
Physiological beta cell death ...... ls in a type-1 diabetes model.
@ast
Physiological beta cell death ...... ls in a type-1 diabetes model.
@en
prefLabel
Physiological beta cell death ...... ls in a type-1 diabetes model.
@ast
Physiological beta cell death ...... ls in a type-1 diabetes model.
@en
P2093
P2860
P356
P1476
Physiological beta cell death ...... ls in a type-1 diabetes model.
@en
P2093
Christophe Benoist
Diane Mathis
Laurent Poirot
Masakazu Hattori
Shannon Turley
P2860
P304
P356
10.1084/JEM.20030966
P407
P577
2003-11-01T00:00:00Z