PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
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Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory.Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex.Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration.Subgenic Pol II interactomes identify region-specific transcription elongation regulatorsPAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and PolyadenylationSystematic identification of Ctr9 regulome in ERα-positive breast cancerCtr9, a key subunit of PAFc, affects global estrogen signaling and drives ERα-positive breast tumorigenesis.Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma.Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells.Drosophila PAF1 Modulates PIWI/piRNA Silencing Capacity.Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.Role of genome guardian proteins in transcriptional elongation.RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II.Ctr9, a Key Component of the Paf1 Complex, Affects Proliferation and Terminal Differentiation in the Developing Drosophila Nervous System.The pol II CTD: new twists in the tail.Pathogenesis of Börjeson-Forssman-Lehmann syndrome: Insights from PHF6 function.Transcription factors that influence RNA polymerases I and II: To what extent is mechanism of action conserved?The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain.O-GlcNAcase Is an RNA Polymerase II Elongation Factor Coupled to Pausing Factors SPT5 and TIF1β.RNF40 regulates gene expression in an epigenetic context-dependent manner.Barcelona conference on epigenetics and cancer 2015: Coding and non-coding functions of the genome.Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.Paf1 Has Distinct Roles in Transcription Elongation and Differential Transcript Fate.CDK9-dependent RNA polymerase II pausing controls transcription initiation.Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome.Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate.The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development.Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA.The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.Emerging Insights into the Roles of the Paf1 Complex in Gene Regulation.PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters.PAF1 regulation of promoter-proximal pause release via enhancer activation.Opposing functions of H2BK120 ubiquitylation and H3K79 methylation in the regulation of pluripotency by the Paf1 complex.BRCA2 Regulates Transcription Elongation by RNA Polymerase II to Prevent R-Loop Accumulation.Chromatin dependencies in cancer and inflammation.Measuring Nascent Transcripts by Nascent-seq.CDK regulation of transcription by RNAP II: Not over 'til it's over?PD2/PAF1 at the Crossroads of the Cancer Network.
P2860
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P2860
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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2015年學術文章
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name
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@ast
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@en
type
label
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@ast
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@en
prefLabel
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@ast
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@en
P2093
P2860
P1433
P1476
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
@en
P2093
Alessandro Gardini
Ali Shilatifard
Ashley R Woodfin
Edwin R Smith
Fei Xavier Chen
Ramin Shiekhattar
Ryan A Rickels
Stacy A Marshall
P2860
P304
P356
10.1016/J.CELL.2015.07.042
P407
P577
2015-08-12T00:00:00Z