Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas. - Wikidata - wikimedia - TriplyDB

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.

http://www.wikidata.org/entity/Q38713523

about

Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma.Distinct molecular profile of diffuse cerebellar gliomas.Fragment-Based Drug Discovery in the Bromodomain and Extra-Terminal Domain Family.Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine Glioma Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma.Positron emission tomography imaging in diffuse intrinsic pontine glioma.HiHiMap: single-cell quantitation of histones and histone posttranslational modifications across the cell cycle by high-throughput imaging.Diffuse Midline Gliomas: Closer to a Cure?Combination of EZH2 inhibitor and BET inhibitor for treatment of diffuse intrinsic pontine glioma.Proteins and Proteoforms: New Separation Challenges.A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.Targeting glioma stem cells through combined BMI1 and EZH2 inhibition.Epigenetic Alterations in Bone and Soft Tissue Tumors.REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.Oncohistones: drivers of pediatric cancers.How many human proteoforms are there?Diffuse Intrinsic Pontine Glioma : Clinical Features, Molecular Genetics, and Novel Targeted Therapeutics.Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.CDK4/6 and PDGFRA Signaling as Therapeutic Targets in Diffuse Intrinsic Pontine Glioma.MutT homolog 1 counteracts the effect of anti-neoplastic treatments in adult and pediatric glioblastoma cells.The developmental origin of brain tumours: a cellular and molecular framework.H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.Untangling the role of mutant histone H3 in diffuse intrinsic pontine glioma.Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity

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Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.

http://www.wikidata.org/entity/Q38713523

description

2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Therapeutic targeting of polyc ...... use intrinsic pontine gliomas.

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type

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Therapeutic targeting of polyc ...... use intrinsic pontine gliomas.

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Therapeutic targeting of polyc ...... use intrinsic pontine gliomas.

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Nature Medicine

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Therapeutic targeting of polyc ...... fuse intrinsic pontine gliomas

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Ali Shilatifard

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Amanda M Saratsis

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Andrea Piunti

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Ashley R Woodfin

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C David James

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Craig M Horbinski

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Emily J Rendleman

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Marc A Morgan

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Nebiyu A Abshiru

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Quanhong Ma

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Hallmarks of Cancer: The Next Generation

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Getting up to speed with transcription elongation by RNA polymerase II

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Targeting bromodomains: epigenetic readers of lysine acetylation

Super-enhancers in the control of cell identity and disease

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

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493-500

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10.1038/NM.4296

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4

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23

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Elizabeth T. Bartom

Alexander V. Misharin

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2017-02-27T00:00:00Z

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28263307

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diffuse intrinsic pontine glioma

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5667640

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