Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation
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Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signalingInterleukin-18 induces rheumatoid arthritis synovial fibroblast CXC chemokine production through NFkappaB activationPurification and characterization of the human interleukin-18 receptorIL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesisOsteoimmunology: interactions of the bone and immune systemAPC-derived cytokines and T cell polarization in autoimmune inflammationInterleukin-18: a therapeutic target in rheumatoid arthritis?Expression of interleukin-18 receptor in fibroblast-like synoviocytesCytokines and direct cell contact in synovitis: relevance to therapeutic interventionBone loss. Therapeutic approaches for preventing bone loss in inflammatory arthritisThe molecular mechanism of osteoclastogenesis in rheumatoid arthritisHost response mechanisms in periodontal diseasesPathophysiological roles for IL-18 in inflammatory arthritisThe effects of interleukin-18 on rat articular chondrocytes: a study of mRNA expression and protein synthesis of proinflammatory substancesInterleukin-18 is regulated by parathyroid hormone and is required for its bone anabolic actionsInterleukin-18.Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage displayInduction of colony-stimulating factor expression following Staphylococcus or Salmonella interaction with mouse or human osteoblastsThe role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.Commitment and differentiation of stem cells to the osteoclast lineage.A proinflammatory role for IL-18 in rheumatoid arthritis.Close association between pulmonary disease manifestation in Mycoplasma pneumoniae infection and enhanced local production of interleukin-18 in the lung, independent of gamma interferonGenetic polymorphisms of cytokine genes in type 2 diabetes mellitus.IL-18 inhibits growth of murine orthotopic prostate carcinomas via both adaptive and innate immune mechanismsInterleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritisInterleukin-18 in hemophagocytic lymphohistiocytosis.Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment.The hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophagesFunctional CD40 expression induced following bacterial infection of mouse and human osteoblasts.Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destructionT-cell involvement in osteoclast biology: implications for rheumatoid bone erosion.Interleukin-17 and interleukin-18 levels in different stages of inflammatory periodontal disease.Gamma interferon (IFN-gamma) and IFN-gamma-inducing cytokines interleukin-12 (IL-12) and IL-18 do not augment infection-stimulated bone resorption in vivo.Interleukin (IL) 18 stimulates osteoclast formation through synovial T cells in rheumatoid arthritis: comparison with IL1 beta and tumour necrosis factor alpha.Blocking of interferon regulatory factor 1 reduces tumor necrosis factor α-induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein a: role of the nuclear interferon regulatory faNegative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors.Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation.Therapeutic potential of targeting IL-1 and IL-18 in inflammation.Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol.Cellular targets of interleukin-18 in rheumatoid arthritis.
P2860
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P2860
Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@ast
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@en
type
label
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@ast
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@en
prefLabel
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@ast
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@en
P2093
P2860
P356
P1476
Interleukin-18 (interferon-gam ...... o inhibit osteoclast formation
@en
P2093
M Kurimoto
T J Chambers
T J Martin
P2860
P304
P356
10.1084/JEM.185.6.1005
P407
P577
1997-03-01T00:00:00Z