Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-gamma signaling complex in human natural killer (NK) cells
about
Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2Regulation of acidification and apoptosis by SHP-1 and Bcl-2G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cellsCell biological steps and checkpoints in accessing NK cell cytotoxicityInhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatasesSLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptorsFunctional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicityRapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signalingThe transmembrane adapter LAT plays a central role in immune receptor signalling.Intracellular signaling by the killer immunoglobulin-like receptors and Ly49.ITAMs versus ITIMs: striking a balance during cell regulation.Human natural killer cell receptors and signal transduction.Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cellsThe immunomodulating roles of glycoproteins in epithelial ovarian cancer.Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity.The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1.A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killingNegative signaling pathways of the killer cell inhibitory receptor and Fc gamma RIIb1 require distinct phosphatases.Copresentation of natural HIV-1 agonist and antagonist ligands fails to induce the T cell receptor signaling cascade.A tale of two TRAPs: LAT and LAB in the regulation of lymphocyte development, activation, and autoimmunityAnalysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.Negative signaling by inhibitory receptors: the NK cell paradigm.Regulation of lymphocyte development and activation by the LAT family of adapter proteins.Natural killer cell education and tolerance.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.Building tolerance by dismantling synapses: inhibitory receptor signaling in natural killer cells.Suppressing the killer instinct.Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity.Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias : combination analysis with cDNA expression array and tissue microarray.SHP-1/immunoreceptor tyrosine-based inhibition motif-independent inhibitory signalling through murine natural killer cell receptor Ly-49A in a transfected B-cell line.Reconstituted killer cell inhibitory receptors for major histocompatibility complex class I molecules control mast cell activation induced via immunoreceptor tyrosine-based activation motifs.Killer cell receptors: keeping pace with MHC class I evolution.Inhibitory receptor signaling destabilizes immunological synapse formation in primary NK cells.Natural killer cells and recognition of MHC class I molecules: new perspectives and challenges in immunology.p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily.
P2860
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P2860
Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-gamma signaling complex in human natural killer (NK) cells
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@ast
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@en
type
label
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@ast
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@en
prefLabel
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@ast
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@en
P2093
P2860
P356
P1476
Killer cell inhibitory recepto ...... uman natural killer (NK) cells
@en
P2093
J H Phillips
L L Lanier
N M Valiante
P2860
P304
P356
10.1084/JEM.184.6.2243
P407
P577
1996-12-01T00:00:00Z