Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity - Wikidata - wikimedia - TriplyDB

Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity

Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity

http://www.wikidata.org/entity/Q28610853

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Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors Constitutive activation of Lck and Fyn tyrosine kinases in large granular lymphocytes infected with the gamma-herpesvirus agents of malignant catarrhal fever DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase Protein Kinase Inhibitors CK59 and CID755673 Alter Primary Human NK Cell Effector Functions The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma Complexity and Diversity of the NKR-P1:Clr (Klrb1:Clec2) Recognition Systems Functional CD32 molecules on human NK cells.The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances Human natural killer cell receptors and signal transduction.Natural killer cell activation in mice and men: different triggers for similar weapons?Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses.Regulation of lymphocyte-mediated killing by GTP-binding proteins.Natural killer cells in patients with severe chronic fatigue syndrome.Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity.In vitro atrazine-exposure inhibits human natural killer cell lytic granule release.BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties.Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis.The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity A balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killing The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing The hemagglutinin-neuramidinase protein of Newcastle disease virus upregulates expression of the TRAIL gene in murine natural killer cells through the activation of Syk and NF-κB Dissecting natural killer cell activation pathways through analysis of genetic mutations in human and mouse.Requirement and redundancy of the Src family kinases Fyn and Lyn in perforin-dependent killing of Cryptococcus neoformans by NK cells Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas.The natural killer cell: a further innate mediator of gouty inflammation?Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells.The role of the cytoskeleton at the immunological synapse.2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.Expression and methylation status of the Syk gene in cervical carcinoma.Novel method for isolating untouched rat natural killer cells with higher purity compared with positive selection and fluorescence-activated cell sorting.A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system.Inhibition of human natural killer cell activity by influenza virions and hemagglutinin Mitogen-activated protein kinase activity is involved in effector functions triggered by the CD94/NKG2-C NK receptor specific for HLA-E.SHP-1/immunoreceptor tyrosine-based inhibition motif-independent inhibitory signalling through murine natural killer cell receptor Ly-49A in a transfected B-cell line.The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing Differential Requirements for Src-Family Kinases in SYK or ZAP70-Mediated SLP-76 Phosphorylation in Lymphocytes.Disturbed expression of the T-cell receptor/CD3 complex and associated signaling molecules in CD30+ T-cell lymphoproliferations.Effects of tributyltin on protein tyrosine kinases and phospholipase C gamma in human natural killer cells.HIV inhibits early signal transduction events triggered by CD16 cross-linking on NK cells, which are important for antibody-dependent cellular cytotoxicity.

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Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity

http://www.wikidata.org/entity/Q28610853

description

1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 1997

@ast

im Dezember 1997 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1997/12/15)

@sk

vědecký článek publikovaný v roce 1997

@cs

wetenschappelijk artikel (gepubliceerd op 1997/12/15)

@nl

наукова стаття, опублікована в грудні 1997

@uk

مقالة علمية (نشرت في 15-12-1997)

@ar

name

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@ast

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@en

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@nl

type

label

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@ast

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@en

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@nl

prefLabel

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@ast

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@en

Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@nl

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JEM.186.12.1965

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Journal of Experimental Medicine

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Functional role for Syk tyrosi ...... -mediated natural cytotoxicity

@en

P2093

B. A. Binstadt

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C. J. Dick

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D. D. Billadeau

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K. M. Brumbaugh

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P. J. Leibson

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R. A. Schoon

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R. M. Ten

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P2860

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C

Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C

APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein

The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions

Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases

A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation

Mechanism of activation for Zap-70 catalytic activity

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

Essential role for ZAP-70 in both positive and negative selection of thymocytes

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1965–1974

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10.1084/JEM.186.12.1965

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12

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186

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13832910

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9396765

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2199178

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