Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
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The long journey to a Systems Biology of neuronal functionPyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibodyNovel delta subunit mutation in slow-channel syndrome causes severe weakness by novel mechanismsIntrinsically low open probability of α7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological temperaturesSynergism at central synapses due to lateral diffusion of transmitter.The effects of geometrical parameters on synaptic transmission: a Monte Carlo simulation study.Quantal transmitter release at somatic motor-nerve terminals: stochastic analysis of the subunit hypothesis.Opening rate of acetylcholine receptor channels.Monte Carlo simulation of miniature endplate current generation in the vertebrate neuromuscular junction.The temperature sensitivity of miniature endplate currents is mostly governed by channel gating: evidence from optimized recordings and Monte Carlo simulations.Finite element simulations of acetylcholine diffusion in neuromuscular junctions.Distribution and turnover rate of acetylcholine receptors throughout the junction folds at a vertebrate neuromuscular junction.Diffusion and binding constants for acetylcholine derived from the falling phase of miniature endplate currents.Desensitization contributes to the synaptic response of gain-of-function mutants of the muscle nicotinic receptor.Evidence that receptors mediating central synaptic potentials extend beyond the postsynaptic density.Rapid activation, desensitization, and resensitization of synaptic channels of crayfish muscle after glutamate pulses.Geometric and many-particle aspects of transmitter binding.Analysis of synaptic transmission in the neuromuscular junction using a continuum finite element model.Photoactivation and dissociation of agonist molecules at the nicotinic acetylcholine receptor in voltage-clamped rat myoballs.The time course of miniature endplate currents and its modification by receptor blockade and ethanol.Analytical description of the activation of multi-state receptors by continuous neurotransmitter signals at brain synapses.Not all partial dopamine D(2) receptor agonists are the same in treating schizophrenia. Exploring the effects of bifeprunox and aripiprazole using a computer model of a primate striatal dopaminergic synapse.Collective binding properties of receptor arrays.A mathematical description of miniature postsynaptic current generation at central nervous system synapses.Kinetic constants of the acetylcholine (ACh) receptor reaction deduced from the rise in open probability after steps in ACh concentration.Kinetics of (+)-tubocurarine blockade at the neuromuscular junctionElevated function of blood clotting factor VIIa mutants that have enhanced affinity for membranes. Behavior in a diffusion-limited reaction.Acetylcholine differentially affects intracellular calcium via nicotinic and muscarinic receptors on the same population of neurons.Post- and prejunctional consequences of ecto-ATPase inhibition: electrical and contractile studies in guinea-pig vas deferens.Bromoacetylcholine and acetylcholinesterase introduced via liposomes into motor nerve endings block increases in quantal size.Novel role for prepatterned nicotinic acetylcholine receptors during myogenesis.Microtransplantation of acetylcholine receptors from normal or denervated rat skeletal muscles to frog oocytes.
P2860
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P2860
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh
1981年學術文章
@zh-hant
name
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@ast
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@en
type
label
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@ast
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@en
prefLabel
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@ast
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@en
P2093
P2860
P356
P1476
Kinetic parameters for acetylcholine interaction in intact neuromuscular junction.
@en
P2093
E E Salpeter
M M Salpeter
P2860
P304
P356
10.1073/PNAS.78.11.7200
P407
P577
1981-11-01T00:00:00Z