The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
about
Pancreatic cancer from bench to bedside: molecular pathways and treatment optionsGenetics and biology of pancreatic ductal adenocarcinomaDevelopmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular OriginGEMMs as preclinical models for testing pancreatic cancer therapiesSWI/SNF chromatin remodeling complexes and cancerAlterations of Epigenetic Regulators in Pancreatic Cancer and Their Clinical ImplicationsPancreatic Cancer, A Mis-interpreter of the Epigenetic LanguageRegulation of Cellular Identity in CancerA rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells.Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous NeoplasmBRG1 promotes hepatocarcinogenesis by regulating proliferation and invasivenessWhole genome expression profiling shows that BRG1 transcriptionally regulates UV inducible genes and other novel targets in human cellsOrganoid models of human and mouse ductal pancreatic cancerReprogramming of human cancer cells to pluripotency for models of cancer progressionBrg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation.The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinomaDynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cellsLoss of SMARCA4 Expression Is Both Sensitive and Specific for the Diagnosis of Small Cell Carcinoma of Ovary, Hypercalcemic TypeThe cis-regulatory switchboard of pancreatic ductal cancer.PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer.The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.Molecular Pathogenesis and Targeted Therapy of Pancreatic Cancer.Molecular mechanism of intraductal papillary mucinous neoplasm and intraductal papillary mucinous neoplasm-derived pancreatic ductal adenocarcinoma.Acinar cell reprogramming: a clinically important target in pancreatic disease.Neat1 is a p53-inducible lincRNA essential for transformation suppression.KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis.p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells.Exploiting receptor tyrosine kinase co-activation for cancer therapy.Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality.Impact of Pdx1-associated chromatin modifiers on islet β-cells.GLI1, a master regulator of the hallmark of pancreatic cancer.Cells of origin of pancreatic neoplasms.Pharmacotherapeutic Management of Pancreatic Ductal Adenocarcinoma: Current and Emerging Concepts.Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer.Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer.Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease.
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P2860
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@ast
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@en
type
label
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@ast
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@en
prefLabel
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@ast
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@en
P2093
P2860
P356
P1433
P1476
The chromatin regulator Brg1 s ...... ncreatic ductal adenocarcinoma
@en
P2093
Akihisa Fukuda
Anke Busch
David W Dawson
Grace E Kim
Holger A Russ
John P Morris Iv
Jorge Ferrer
Klemens J Hertel
Matthew A Firpo
Matthias Hebrok
P2860
P2888
P304
P356
10.1038/NCB2916
P577
2014-02-23T00:00:00Z