Role of epigenetic modifications in normal globin gene regulation and butyrate-mediated induction of fetal hemoglobin.
about
Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathiesEpigenetic regulation of fetal globin gene expression in adult erythroid cellsNuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.Gum Arabic as fetal hemoglobin inducing agent in sickle cell anemia; in vivo study.FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors.The switch from fetal to adult hemoglobinInduction of human fetal hemoglobin expression by adenosine-2',3'-dialdehyde.Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemiaDifferences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease.Epigenetics of beta-globin gene regulationInvestigational drugs in sickle cell anemia.Novel approaches to the treatment of sickle cell disease: the potential of histone deacetylase inhibitors.Can nutritional modulation of maternal intestinal microbiota influence the development of the infant gastrointestinal tract?Gamma reactivation using the spongy effect of KLF1-binding site sequence: an approach in gene therapy for beta-thalassemia.siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures.Thalidomide is more efficient than sodium butyrate in enhancing GATA-1 and EKLF gene expression in erythroid progenitors derived from HSCs with β-globin gene mutation.Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human beta-globin locus.The role of epigenetics in the induction of fetal hemoglobin: a combination therapy approach.Differential requirement of a distal regulatory region for pre-initiation complex formation at globin gene promoters.Pharmacological and molecular approaches for the treatment of β-hemoglobin disorders.Histone deacetylase 1 activates PU.1 gene transcription through regulating TAF9 deacetylation and transcription factor IID assembly.Suppression of Spleen Tyrosine Kinase (Syk) by Histone Deacetylation Promotes, Whereas BAY61-3606, a Synthetic Syk Inhibitor Abrogates Colonocyte Apoptosis by ERK Activation.
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P2860
Role of epigenetic modifications in normal globin gene regulation and butyrate-mediated induction of fetal hemoglobin.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@ast
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@en
type
label
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@ast
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@en
prefLabel
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@ast
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@en
P2093
P2860
P1433
P1476
Role of epigenetic modificatio ...... induction of fetal hemoglobin.
@en
P2093
George F Atweh
Hassana Fathallah
Millicent Sutton
Rona S Weinberg
Yelena Galperin
P2860
P304
P356
10.1182/BLOOD-2007-02-076091
P407
P577
2007-07-17T00:00:00Z