Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines. - Wikidata - wikimedia - TriplyDB

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

http://www.wikidata.org/entity/Q36385484

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The Case for Live Attenuated Vaccines against the Neglected Zoonotic Diseases Brucellosis and Bovine Tuberculosis Towards an HIV cure based on targeted killing of infected cells: different approaches against acute versus chronic infection Host-pathogen interaction in HIV infection A global approach to HIV-1 vaccine development HIV vaccine development: strategies for preclinical and clinical investigation Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques Characterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profiling Rectal HSV-2 Infection May Increase Rectal SIV Acquisition Even in the Context of SIVΔnef Vaccination CD8 T cell response maturation defined by anentropic specificity and repertoire depth correlates with SIVΔnef-induced protection Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo Long-term central and effector SHIV-specific memory T cell responses elicited after a single immunization with a novel lentivector DNA vaccine DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent Virus Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine HIV-1 vaccines: challenges and new perspectives Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.Vaccine-induced myeloid cell population dampens protective immunity to SIV Development of replication-competent viral vectors for HIV vaccine delivery.Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates.Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection.Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens.Analysis of HLA A*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial.Host factors determine differential disease progression after infection with nef-deleted simian immunodeficiency virus Immune activation and HIV persistence: implications for curative approaches to HIV infection.A CD4+ T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cell function.Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells.Transcriptional profiling of peripheral CD8+T cell responses to SIVΔnef and SIVmac251 challenge reveals a link between protective immunity and induction of systemic immunoregulatory mechanisms.Superior control of HIV-1 replication by CD8+ T cells targeting conserved epitopes: implications for HIV vaccine design Repressive effect of primary virus replication on superinfection correlated with gut-derived central memory CD4(+) T cells in SHIV-infected Chinese rhesus macaques Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques.B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults Multimodality vaccination against clade C SHIV: partial protection against mucosal challenges with a heterologous tier 2 virus.Early biodistribution and persistence of a protective live attenuated SIV vaccine elicits localised innate responses in multiple lymphoid tissues PAS-positive extracellular deposits within germinal centers of hyperplastic follicles during SIV infection in a rhesus macaque.In Situ Staining and Laser Capture Microdissection of Lymph Node Residing SIV Gag-Specific CD8+ T cells--A Tool to Interrogate a Functional Immune Response Ex Vivo.Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

http://www.wikidata.org/entity/Q36385484

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

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Adrian McDermott

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Alfred W Legasse

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Andrew Sylwester

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Andrew T Smith

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Eisa Mahyari

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Francois Lefebvre

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Haesun Park

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Jeffrey D Lifson

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Jin Young Bae

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Kelli Oswald

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Bioconductor: open software development for computational biology and bioinformatics

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

Retroviral superinfection resistance.

A new description of cellular quiescence

Revealing the role of CD4(+) T cells in viral immunity

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

Follicular helper CD4 T cells (TFH)

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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10.1038/NM.2934

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11

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18

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David C Montefiori

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2012-09-09T00:00:00Z

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230825862

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22961108

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attenuated vaccine

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3493820

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