Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity.
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Therapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseasesP53-MDM2 Pathway: Evidences for A New Targeted Therapeutic Approach in B-Acute Lymphoblastic LeukemiaCombining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapyClinical utility of lenalidomide in the treatment of myelodysplastic syndromesNegative regulation of the p300-p53 interplay by DDX24.p53-dependent SIRT6 expression protects Aβ42-induced DNA damage.The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption.p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?Mechanisms of proteasome inhibitor-induced cytotoxicity in malignant glioma.Genetic susceptibility to cervical cancer: role of common polymorphisms in apoptosis-related genes.Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 statusChanges in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells.Effects of HAb18G/CD147 knockout on hepatocellular carcinoma cells in vitro using a novel zinc-finger nuclease-targeted gene knockout approach.Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes.Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness.Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy.The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants.Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.Molecular mechanisms involving prostate cancer racial disparity.The Role of MDM2 in Promoting Genome Stability versus Instability.The 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction.The Roles of P53 and its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis Stage Mouse Embryos.The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia.p53 and Mdm2 act synergistically to maintain cardiac homeostasis and mediate cardiomyocyte cell cycle arrest through a network of microRNAs.Individual and combined effect of TP53, MDM2, MDM4, MTHFR, CCR5, and CASP8 gene polymorphisms in lung cancer.Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma.Different TP53 mutants in p53 overexpressed epithelial ovarian carcinoma can be associated both with altered and unaltered glycolytic and apoptotic profiles.MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers.Valproic Acid Exposure of Pregnant Rats During Organogenesis Disturbs Pancreas Development in Insulin Synthesis and Secretion of the Offspring.CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer.Association of p53 and mdm2 in the development and progression of non-small cell lung cancer.20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors.Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.TP53 mutations and SNPs as prognostic and predictive factors in patients with breast cancer.Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System'-GlcNAc Code' Mediated Biological Functions of Downstream ProteinsEtoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation
P2860
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P2860
Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@ast
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@en
type
label
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@ast
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@en
prefLabel
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@ast
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@en
P2860
P921
P356
P1433
P1476
Dual Roles of MDM2 in the Regu ...... M2 Repression of p53 Activity.
@en
P2093
P2860
P304
P356
10.1177/1947601912455199
P577
2012-03-01T00:00:00Z