Repression of p53-mediated transcription by MDM2: a dual mechanism
about
Explaining oscillations and variability in the p53-Mdm2 systemRBB, a novel transcription repressor, represses the transcription of HDM2 oncogeneIdentification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domainsThe Mdm2 oncoprotein interacts with the cell fate regulator NumbAdenovirus E1B 55K represses p53 activation in vitro.p53 Stimulates TFIID-TFIIA-promoter complex assembly, and p53-T antigen complex inhibits TATA binding protein-TATA interactionMDM2 suppresses p73 function without promoting p73 degradationInhibition of HDM2 and activation of p53 by ribosomal protein L23Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activationRibosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathwayCancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradationBRCA1 regulates p53-dependent gene expressionMDM2 negatively regulates the human telomerase RNA gene promoterInhibition of human esophageal squamous cell carcinomas by targeted silencing of tumor enhancer genes: an overviewStructure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding ProteinMdm2 as a chromatin modifierMDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylationTranscription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SONA novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingersQSAR: hydropathic analysis of inhibitors of the p53-mdm2 interaction.C-terminal ubiquitination of p53 contributes to nuclear exportMdm2: the ups and downs.Oridonin induces G2/M cell cycle arrest and apoptosis via the PI3K/Akt signaling pathway in hormone-independent prostate cancer cells.Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.Molecular interaction map of the mammalian cell cycle control and DNA repair systems.The p53 pathway and apoptosis.Even-skipped represses transcription by binding TATA binding protein and blocking the TFIID-TATA box interaction.mdm2: a bridge over the two tumour suppressors, p53 and Rb.microRNAs and Alu elements in the p53-Mdm2-Mdm4 regulatory network.Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication.Single-nucleotide polymorphism (c.309T>G) in the MDM2 gene and lung cancer riskNew insights into the mechanism of inhibition of p53 by simian virus 40 large T antigenAlleviation of human papillomavirus E2-mediated transcriptional repression via formation of a TATA binding protein (or TFIID)-TFIIB-RNA polymerase II-TFIIF preinitiation complex.Tumor suppressor p53 is required to modulate BRCA1 expression.Myc proteins as therapeutic targets.Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonismMDM2 recruitment of lysine methyltransferases regulates p53 transcriptional outputMdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.Tumor suppression and normal aging in mice with constitutively high p53 activity.
P2860
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P2860
Repression of p53-mediated transcription by MDM2: a dual mechanism
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Repression of p53-mediated transcription by MDM2: a dual mechanism
@ast
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en-gb
Repression of p53-mediated transcription by MDM2: a dual mechanism
@nl
type
label
Repression of p53-mediated transcription by MDM2: a dual mechanism
@ast
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en-gb
Repression of p53-mediated transcription by MDM2: a dual mechanism
@nl
prefLabel
Repression of p53-mediated transcription by MDM2: a dual mechanism
@ast
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en-gb
Repression of p53-mediated transcription by MDM2: a dual mechanism
@nl
P2093
P2860
P3181
P356
P1433
P1476
Repression of p53-mediated transcription by MDM2: a dual mechanism
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.11.15.1974
P407
P577
1997-08-01T00:00:00Z