about
Computational enzyme design approaches with significant biological outcomes: progress and challengesTesting Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion HoleUsing affinity chromatography to engineer and characterize pH-dependent protein switchesComputational Design of the Sequence and Structure of a Protein-Binding PeptideComputational reverse-engineering of a spider-venom derived peptide active against Plasmodium falciparum SUB1Computational protein design: the Proteus software and selected applications.Direct prediction of profiles of sequences compatible with a protein structure by neural networks with fragment-based local and energy-based nonlocal profilesProtein deimmunization via structure-based design enables efficient epitope deletion at high mutational loadsComputational tools for epitope vaccine design and evaluationPROTDES: CHARMM toolbox for computational protein design.The Framework of Computational Protein Design.Parallel Computational Protein Design.Designing specific protein-protein interactions using computation, experimental library screening, or integrated methodsDead-end elimination with perturbations (DEEPer): a provable protein design algorithm with continuous sidechain and backbone flexibility.Conformational diversity and computational enzyme designCapturing protein sequence-structure specificity using computational sequence design.Evaluation of an inverse molecular design algorithm in a model binding siteTransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis.Toward accurate screening in computer-aided enzyme design.Engineering a protein-protein interface using a computationally designed libraryExperimental library screening demonstrates the successful application of computational protein design to large structural ensemblesAn efficient parallel algorithm for accelerating computational protein design.PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimalityA generic program for multistate protein design.Structural informatics, modeling, and design with an open-source Molecular Software Library (MSL).PROTS-RF: a robust model for predicting mutation-induced protein stability changes.Improving computational protein design by using structure-derived sequence profile.Computational design of affinity and specificity at protein-protein interfacesThe scoring of poses in protein-protein docking: current capabilities and future directionsApplying physics-based scoring to calculate free energies of binding for single amino acid mutations in protein-protein complexesDesign of a zinc-finger hydrolase with a synthetic αββ protein.Antibody engineering for increased potency, breadth and half-life.Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo.Adding energy minimization strategy to peptide-design algorithm enables better search for RNA-binding peptides: Redesigned λ N peptide binds boxB RNA.Computer-aided antibody design.A critical analysis of computational protein design with sparse residue interaction graphs.Engineering de novo disulfide bond in bacterial α-type carbonic anhydrase for thermostable carbon sequestrationThe empirical valence bond as an effective strategy for computer-aided enzyme design.Biomolecular simulation and modelling: status, progress and prospects.The Tumbleweed: towards a synthetic proteinmotor.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Progress in computational protein design.
@ast
Progress in computational protein design.
@en
type
label
Progress in computational protein design.
@ast
Progress in computational protein design.
@en
prefLabel
Progress in computational protein design.
@ast
Progress in computational protein design.
@en
P2860
P1476
Progress in computational protein design.
@en
P2093
Bruce Tidor
Shaun M Lippow
P2860
P304
P356
10.1016/J.COPBIO.2007.04.009
P577
2007-07-20T00:00:00Z