Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II - Wikidata - wikimedia - TriplyDB

Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II

Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II

http://www.wikidata.org/entity/Q36399471

about

Regulating the immune system: the induction of regulatory T cells in the periphery Insights into type 1 diabetes from the autoimmune polyendocrine syndromes IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelination CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis.Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node.Epigenetic control of the foxp3 locus in regulatory T cells FOXP3 promoter demethylation reveals the committed Treg population in humans.Selective depletion of regulatory T cell subsets by docetaxel treatment in patients with nonsmall cell lung cancer Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis.The changing microbial environment and chronic inflammatory disorders.Decreased numbers of blood dendritic cells and defective function of regulatory T cells in antineutrophil cytoplasmic antibody-associated vasculitis Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation.Infection, immunoregulation, and cancer.The role of X-linked FOXP3 in the autoimmune susceptibility of Turner Syndrome patients Microbes, immunoregulation, and the gut.Vaccines against myasthenia gravis.Regulatory T cell kinetics in the peripheral blood of patients with Crohn's disease.Human FoxP3(+)CD4(+) regulatory T cells: their knowns and unknowns.The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders.Defective regulatory and effector T cell functions in patients with FOXP3 mutations.Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells.Can mesenchymal stem cells reverse chronic stress-induced impairment of lung healing following traumatic injury?Low telomerase activity in CD4+ regulatory T cells in patients with severe chronic GVHD after hematopoietic stem cell transplantation.Enrichment of CD4+ CD25high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids.Autoimmune polyglandular syndrome Type 2: the tip of an iceberg?Functional avidity directs T-cell fate in autoreactive CD4+ T cells.Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells.Lymphocytes, neuropeptides, and genes involved in alopecia areata.Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype.Clinical application of human CD4+ CD25+ regulatory T cells for the treatment of inflammatory bowel diseases.Human regulatory T cells: a unique, stable thymic subset or a reversible peripheral state of differentiation?Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus.Regulatory T cells in immunologic self-tolerance and autoimmune disease.Regulatory T-cells in chronic lymphocytic leukemia and autoimmune diseases Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells.Imbalance of regulatory T cells in human autoimmune diseases.Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis.Regulatory T cells in human disease and their potential for therapeutic manipulation.

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P2860

Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II

http://www.wikidata.org/entity/Q36399471

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

Defective suppressor function ...... polyglandular syndrome type II

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Defective suppressor function ...... polyglandular syndrome type II

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type

label

Defective suppressor function ...... polyglandular syndrome type II

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Defective suppressor function ...... polyglandular syndrome type II

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prefLabel

Defective suppressor function ...... polyglandular syndrome type II

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Defective suppressor function ...... polyglandular syndrome type II

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Journal of Experimental Medicine

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Defective suppressor function ...... polyglandular syndrome type II

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Christoph Gabler

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Hanns-Martin Lorenz

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Joachim R Kalden

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Martin A Kriegel

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Norbert Blank

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Tobias Lohmann

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P2860

Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

Control of regulatory T cell development by the transcription factor Foxp3

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Projection of an immunological self shadow within the thymus by the aire protein

An essential role for Scurfin in CD4+CD25+ T regulatory cells

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance.

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.

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1285-1291

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10.1084/JEM.20032158

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9

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199

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8587264

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15117972

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2211900

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