Interleukin 6 is required for the development of collagen-induced arthritis - Wikidata - wikimedia - TriplyDB

Interleukin 6 is required for the development of collagen-induced arthritis

Interleukin 6 is required for the development of collagen-induced arthritis

http://www.wikidata.org/entity/Q36400353

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JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130 APC-derived cytokines and T cell polarization in autoimmune inflammation IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathways A proinflammatory role for Fas in joints of mice with collagen-induced arthritis The role and clinical implications of G6PI in experimental models of rheumatoid arthritis Leptin in septic arthritis: decreased levels during infection and amelioration of disease activity upon its administration Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice Accelerated development of arthritis in mice lacking endothelial selectins.Endothelial Dysfunction and Inflammation: Immunity in Rheumatoid Arthritis Animal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside-a Comprehensive Review The Role of the Transcriptional Regulation of Stromal Cells in Chronic Inflammation Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing Spotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to date Inflammation induced loss of skeletal muscle Pathophysiological roles for IL-18 in inflammatory arthritis Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis The effects of interleukin-18 on rat articular chondrocytes: a study of mRNA expression and protein synthesis of proinflammatory substances Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis Oxidized phospholipids induce changes in hepatic paraoxonase and ApoJ but not monocyte chemoattractant protein-1 via interleukin-6.Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice.Lack of IL-6 during coxsackievirus infection heightens the early immune response resulting in increased severity of chronic autoimmune myocarditis.Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis.Endogenous interleukin-6 plays a crucial protective role in streptococcal toxic shock syndrome via suppression of tumor necrosis factor alpha production.Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation.Interleukin-6 induces Gr-1+CD11b+ myeloid cells to suppress CD8+ T cell-mediated liver injury in mice Expression of interleukin 6 in brain and colon of rats with TNBS-induced colitis.Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice.Anti-interleukin 6 receptor antibody treatment in rheumatic disease.Interleukin-6 and rheumatic diseases.Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia IL-6 in inflammation, immunity, and disease Interleukin-1β and interleukin-6 in arthritis animal models: roles in the early phase of transition from acute to chronic inflammation and relevance for human rheumatoid arthritis gp130 at the nexus of inflammation, autoimmunity, and cancer.

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P2860

Interleukin 6 is required for the development of collagen-induced arthritis

http://www.wikidata.org/entity/Q36400353

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1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年學術文章

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1998年學術文章

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1998年學術文章

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name

Interleukin 6 is required for the development of collagen-induced arthritis

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Interleukin 6 is required for the development of collagen-induced arthritis

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type

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Interleukin 6 is required for the development of collagen-induced arthritis

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Interleukin 6 is required for the development of collagen-induced arthritis

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prefLabel

Interleukin 6 is required for the development of collagen-induced arthritis

@ast

Interleukin 6 is required for the development of collagen-induced arthritis

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Interleukin 6 is required for the development of collagen-induced arthritis

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P2860

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

Role of cytokines in rheumatoid arthritis

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis

Interleukin-6 and its receptor: a paradigm for cytokines.

Defective development of pristane-oil-induced plasmacytomas in interleukin-6-deficient BALB/c mice.

Genetic susceptibility to murine collagen II autoimmune arthritis. Proposed relationship to the IgG2 autoantibody subclass response, complement C5, major histocompatibility complex (MHC) and non-MHC loci

Mouse plasmacytoma growth in vivo: enhancement by interleukin 6 (IL-6) and inhibition by antibodies directed against IL-6 or its receptor.

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187

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2212160

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