Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
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Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signalingBiased and g protein-independent signaling of chemokine receptorsPathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases.Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.Constitutive signaling by Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor desensitizes calcium mobilization by other receptors.Sulfotyrosines of the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promote tumorigenesis through autocrine activationActivation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesisTransgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma.Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery.Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.Virally encoded 7TM receptors.Antiviral potential of chemokines.The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashionPatterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirusA G protein-coupled receptor encoded by rhesus rhadinovirus is similar to ORF74 of Kaposi's sarcoma-associated herpesvirus.Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse.HHV-8 infection: a model for reactivation and transmission.HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathwayActivity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Recombinant Murine Gamma Herpesvirus 68 Carrying KSHV G Protein-Coupled Receptor Induces Angiogenic Lesions in MiceOncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis.Chemokine receptor internalization and intracellular trafficking.Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma.Investigational agents for treatment of AIDS-related Kaposi's sarcoma.Kaposi's sarcoma-associated herpesvirus-G protein-coupled receptor-expressing endothelial cells exhibit reduced migration and stimulated chemotaxis by chemokine inverse agonistsChemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture.Targeted therapy for Kaposi sarcoma.The Epstein-Barr virus BILF1 gene encodes a G protein-coupled receptor that inhibits phosphorylation of RNA-dependent protein kinase.New drug targets in Kaposi sarcoma.Pharmacological management of Kaposi's sarcoma.Hijacking GPCRs by viral pathogens and tumor.Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via G(i) and phospholipase C-dependent signaling pathways.The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells.KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2.The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins.Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8 g protein-coupled receptor.G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR.Differential activation of murine herpesvirus 68- and Kaposi's sarcoma-associated herpesvirus-encoded ORF74 G protein-coupled receptors by human and murine chemokines
P2860
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P2860
Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@ast
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@en
type
label
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@ast
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@en
prefLabel
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@ast
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@en
P2093
P2860
P356
P1476
Human interferon-gamma-inducib ...... rus G protein-coupled receptor
@en
P2093
E Geras-Raaka
I Clark-Lewis
M C Gershengorn
P2860
P304
P356
10.1084/JEM.188.2.405
P407
P577
1998-07-01T00:00:00Z