The Epstein-Barr virus BILF1 gene encodes a G protein-coupled receptor that inhibits phosphorylation of RNA-dependent protein kinase.
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Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonistMolecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activityThe Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradationMolecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases.A locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteinsThe Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning.Virus and cell RNAs expressed during Epstein-Barr virus replicationUnexpected patterns of Epstein-Barr virus transcription revealed by a high throughput PCR array for absolute quantification of viral mRNA.Identification and functional comparison of seven-transmembrane G-protein-coupled BILF1 receptors in recently discovered nonhuman primate lymphocryptoviruses.Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptorsEBV BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail.The chemokine receptor homologue encoded by US27 of human cytomegalovirus is heavily glycosylated and is present in infected human foreskin fibroblasts and enveloped virus particles.Modulation of autophagy-like processes by tumor viruses.Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunityStructural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors-A Consequence of Evolutionary Pressure?Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?CXCR4: a virus's best friend?Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5).The future of antiviral immunotoxins.Hijacking GPCRs by viral pathogens and tumor.EBV glycoproteins: where are we now?Manipulation of the host cell membrane by human γ-herpesviruses EBV and KSHV for pathogenesis.Diverse mechanisms evolved by DNA viruses to inhibit early host defenses.The Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I molecules trafficking on both the exocytic and endocytic pathwaysEpstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-κB signaling during productive replication.Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells.Cooperation between Epstein-Barr virus immune evasion proteins spreads protection from CD8+ T cell recognition across all three phases of the lytic cycle.Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor prevents AU-rich-element-mediated mRNA decay.Epstein-Barr virus-host cell interactions: an epigenetic dialog?Innate immune modulation in EBV infection.Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma.The Immunomodulatory Capacity of an Epstein-Barr Virus Abortive Lytic Cycle: Potential Contribution to Viral Tumorigenesis.
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The Epstein-Barr virus BILF1 gene encodes a G protein-coupled receptor that inhibits phosphorylation of RNA-dependent protein kinase.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2005
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
@en
The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
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type
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The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
@en
The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
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prefLabel
The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
@en
The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
@nl
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The Epstein-Barr virus BILF1 g ...... RNA-dependent protein kinase.
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Cathrien A Bruggeman
Cornelis Vink
Erik Beuken
Martine J Smit
Patrick S Beisser
Yvonne K Gruijthuijsen
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P304
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10.1128/JVI.79.1.441-449.2005
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P577
2005-01-01T00:00:00Z